Axonal branching pattern and coupling mechanisms of the cerebral giant neurones in the snail, Lymnaea stagnalis

Journal of Neurobiology
J T GoldschmedingJ C Lodder

Abstract

The axonal branching pattern of the two cerebral giant neurones (CGCs) of Lymnaea stagnalis was studied with intrasomatically applied horseradish peroxidase. The cells are symmetrical. Each CGC projects to the ipsilateral n. labialis medius and n. arteriae labialis, the subcerebral commissure, and to all ipsi- and contralateral buccal nerves. The contralateral buccal nerves are reached via the ipsilateral cerebro-buccal connective and the buccal commissure. The CGC fire action potentials 1:1 in a driver-follower relationship. Each cell is capable of both driving and following. The relationship depends on the membrane potentials of the somata. In driving CGC spikes are initiated in a cerebral spike trigger zone located near the soma. In following cells spikes are initiated in a distal zone located in the buccal ganglia. The buccal zone is only affected by the partner CGC. CGC are synchronized by three coupling mechanisms: mutual excitatory chemical synapses, electrotonic coupling, and common input. The chemical and electrotonic connections are located in the buccal ganglia. All spikes are relayed to the partner cell via the chemical synapses. The electrotonic coupling improves the efficiency of the chemical synapses. The dual co...Continue Reading

References

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Citations

Jan 1, 1984·Progress in Neurobiology·K S Rózsa
Jan 1, 1988·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·V FloresJ P Saavedra
Jan 1, 1983·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·A Barber
Feb 28, 2002·The European Journal of Neuroscience·Kevin StarasGyörgy Kemenes
Sep 30, 2003·Reviews in the Neurosciences·Ronald E van Kesteren, Gaynor E Spencer
Nov 16, 2006·Analytical Chemistry·Bhavik Anil PatelDanny O'Hare

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