Axonal variants of Guillain-Barré syndrome: an update.

Journal of Neurology
Pei ShangHong-Liang Zhang

Abstract

Axonal variants of Guillain-Barré syndrome (GBS) mainly include acute motor axonal neuropathy, acute motor and sensory axonal neuropathy, and pharyngeal-cervical-brachial weakness. Molecular mimicry of human gangliosides by a pathogen's lipooligosaccharides is a well-established mechanism for Campylobacter jejuni-associated GBS. New triggers of the axonal variants of GBS (axonal GBS), such as Zika virus, hepatitis viruses, intravenous administration of ganglioside, vaccination, and surgery, are being identified. However, the pathogenetic mechanisms of axonal GBS related to antecedent bacterial or viral infections other than Campylobacter jejuni remain unknown. Currently, autoantibody classification and serial electrophysiology are cardinal approaches to differentiate axonal GBS from the prototype of GBS, acute inflammatory demyelinating polyneuropathy. Newly developed technologies, including metabolite analysis, peripheral nerve ultrasound, and feature selection via artificial intelligence are facilitating more accurate diagnosis of axonal GBS. Nevertheless, some key issues, such as genetic susceptibilities, remain unanswered and moreover, current therapies bear limitations. Although several therapies have shown considerable be...Continue Reading

References

Mar 25, 1978·British Medical Journal·N A Sliman
Nov 28, 1992·BMJ : British Medical Journal·A FiguerasJ R Laporte
Jan 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·T E Feasby
May 1, 1988·Annals of Neurology·A A IlyasG M McKhann
Dec 1, 1986·Brain : a Journal of Neurology·T E FeasbyD W Zochodne
Jun 1, 1984·American Journal of Epidemiology·J G Breman, N S Hayner
Jan 1, 1993·Neuroepidemiology·E Díez-TejedorA Gil-Peralta
Apr 1, 1996·Journal of the Neurological Sciences·V GovoniV C Monetti
Jun 1, 2000·Journal of the Neurological Sciences·M OdakaK Hirata
Sep 27, 2000·Brain : a Journal of Neurology·M MoriT Hattori
Apr 18, 2001·European Neurology·F G Van der MechéUNKNOWN GBS-consensus group of the Dutch Neuromuscular Research Support Centre
Aug 2, 2001·Archives of Neurology·D M Green, A H Ropper
Dec 4, 2002·Experimental Neurology·Hiroyuki WakisakaSeiji Matsuda
Jul 28, 2004·Proceedings of the National Academy of Sciences of the United States of America·Nobuhiro YukiMitsunori Yamada
Aug 22, 2006·CNS & Neurological Disorders Drug Targets·Tomoko Komagamine, Nobuhiro Yuki
Nov 24, 2007·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·A Créange
Jan 11, 2008·Brain : a Journal of Neurology·Susan K HalsteadHugh J Willison
Apr 9, 2008·Bone Marrow Transplantation·F OstronoffK C Hsu
Oct 11, 2008·Journal of the Peripheral Nervous System : JPNS·Susan K HalsteadHugh J Willison
Oct 14, 2008·Lancet Neurology·Pieter A van DoornBart C Jacobs
Dec 18, 2008·Neuroepidemiology·Anita McGroganCorinne S de Vries
Apr 25, 2009·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Penina HaberFrank DeStefano
Dec 8, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·Ricardo D LardoneGustavo A Nores
Apr 17, 2010·Journal of Clinical Immunology·Pieter A van DoornBart C Jacobs
Apr 30, 2010·Neurocritical Care·Marko KutlesaBruno Barsić
Sep 28, 2010·Journal of Neurology, Neurosurgery, and Psychiatry·Antonino UnciniMargherita Capasso
Jan 29, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Judith DrenthenBart C Jacobs
Mar 23, 2011·Neuroepidemiology·James J SejvarOliver W Morgan
Jul 30, 2011·Glycobiology·Aliaksei V PukinHan Zuilhof
Sep 29, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Hiromichi SakaiNobuhiro Yuki

❮ Previous
Next ❯

Citations

May 14, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Donatella OttavianiBruno Giometto
Oct 29, 2020·Expert Review of Clinical Immunology·Pei ShangHong-Liang Zhang
Mar 2, 2021·Lancet·Nortina ShahrizailaSatoshi Kuwabara
May 11, 2021·Autoimmunity Reviews·Ozlem Saritas NakipBenan Bayrakci
May 18, 2021·Frontiers in Pharmacology·Pei ShangHong-Liang Zhang
Jul 12, 2021·Journal of Neuroimmunology·Shaghayegh KhanmohammadiNima Rezaei

❮ Previous
Next ❯

Related Concepts

Related Feeds

Campylobacteriosis (ASM)

Campylobacteriosis is caused by the bacteria Campylobacter jejuni and is a common cause of gastroenteritis in humans. Discover the latest research on Campylobacteriosis here.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Steve VucicD R Cornblath
Acta Neurologica Scandinavica
María J SedanoJosé Berciano
© 2021 Meta ULC. All rights reserved