PMID: 6411926Sep 1, 1983Paper

Aza analogues of lucanthone: synthesis and antitumor and bactericidal properties

Journal of Medicinal Chemistry
M Croisy-Delcey, E Bisagni

Abstract

Three types of aza analogues of lucanthone were synthesized for evaluation as antitumor drugs. None of the compounds was found to have significant cytotoxic effects either on Friend tumor cells or on L1210 leukemia cells. However, one of the target compounds, 5,10-dihydro-10-oxo-1-[[3-(diethylamino)propyl]amino]-3-methylpyrido [4,3-b]quinoline, was shown to have noticeable antibiotic properties.

Citations

Dec 1, 1992·Journal of Molecular Recognition : JMR·C BaillyC Houssier
Jan 1, 1986·Journal of Cancer Research and Clinical Oncology·H Osswald, M Youssef
Feb 22, 2008·Journal of Medicinal Chemistry·Yuhpyng L ChenDavid W Schulz
May 7, 2010·Journal of Combinatorial Chemistry·Chang-Sheng YaoShu-Jiang Tu

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