Azthreonam activity against gram-negative bacilli

Chemotherapy
D A Bremner

Abstract

The in vitro activity of azthreonam - a monocyclic beta-lactam antibiotic - was compared with the activities of ampicillin, cephalothin, cefuroxime, cefotaxime, cefoperazone, lamoxactam, ceftazidime, and N-formimidoyl thienamycin against 249 clinical isolates of gram-negative bacilli. Azthreonam was as active or more active than all the third-generation cephalosporins against all the Enterobacteriaceae except Klebsiella. Against Klebsiella azthreonam was more active than cefoperazone but less active than the other third-generation cephalosporins. Azthreonam, ceftazidime, and piperacillin were equally active against Pseudomonas aeruginosa.

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.