B and T cell markers of bone marrow and peripheral blood lymphoid cells in patients with paraproteinaemia

Acta Haematologica
S HuszN Simon

Abstract

Studies have been carried out on B and T cells in bone marrow and peripheral blood from patients with paraproteinaemia. The peripheral blood of patients with multiple myeloma showed a significant increase of B cells, mainly lymphoid cells bearing immunoglobulins corresponding to the paraproteins, while in patients with benign monoclonal gammopathy only a slight increase of B cells and a moderate decrease of T cells have been found. As to the bone marrow, the B cell population was significantly raised in patients with multiple myeloma, but it remained unchanged in patients with benign monoclonal gammopathy. Our findings may offer a new possibility to distinguish between these two diseases and provide further data to their pathogenesis.

Citations

Oct 1, 1992·Contact Dermatitis·A R HalbertL M Wall
Apr 24, 2008·Toxicology and Industrial Health·Selene ChouChristopher De Rosa
Jan 1, 1993·Critical Reviews in Toxicology·J J HostýnekR H Guy
May 4, 2010·Contact Dermatitis·Halvor Möller
Jun 25, 2015·Contact Dermatitis·David BregnbakJacob P Thyssen
Jul 1, 1984·Scandinavian Journal of Haematology·A NaessC O Solberg

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