B-cell lymphoma in the peripheral nerves of a cat

Veterinary Pathology
M A HigginsM Kiupel

Abstract

A B-cell, Burkitt-type lymphoma, diffusely affecting the peripheral nerves and intramuscular nerve branches was diagnosed in a 4-year-old domestic shorthair cat with a chronic progressive history of flaccid tetraparesis and generalized muscle atrophy. There was no evidence of cranial nerve, central nervous system, radicular, bone marrow, splenic, or lymph node involvement. The cat tested negative for feline retroviruses and a wide variety of herpes viruses, including Epstein-Barr virus. The clinical manifestation of this case was similar to the chronic polyneuropathic variant of human diffuse neurolymphomatosis; a condition most commonly caused by an axonopathy resulting from infiltration of peripheral nerves with non-Hodgkin's lymphoma.

References

Mar 1, 1975·Australian Veterinary Journal·J G Allen, T Amis
Mar 1, 1994·Journal of Veterinary Internal Medicine·S B LaneJ E Oliver
Jul 1, 1996·Journal of Clinical Microbiology·D R VanDevanterT M Rose
Nov 21, 1998·Veterinary Pathology·D FondevilaM Pumarola
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Nov 6, 2003·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·R J MellanbyM E Herrtage
Nov 16, 2004·Muscle & Nerve·John J Kelly, Donald S Karcher

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Citations

Jun 12, 2014·Journal of Comparative Pathology·A LehmbeckerA Beineke
Mar 11, 2016·The Journal of Veterinary Medical Science·Masashi SakuraiTakehito Morita
Oct 1, 2016·The Veterinary Journal·Maria Teresa MandaraPietro Calò
Sep 12, 2012·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Luciana MandrioliMaria Elena Turba
Jan 13, 2009·Journal of Feline Medicine and Surgery·Helge LinzmannRobert Klopfleisch
Mar 5, 2019·JFMS Open Reports·Michaela J BeasleyJennifer M Gambino

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Methods Mentioned

BETA
PCR
biopsy
biopsies

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