BaAMPs: the database of biofilm-active antimicrobial peptides

Biofouling
Mariagrazia Di LucaGiovanna Batoni

Abstract

Antimicrobial peptides (AMPs) are increasingly being considered as novel agents against biofilms. The development of AMP-based anti-biofilm strategies strongly relies on the design of sequences optimized to target specific features of sessile bacterial/fungal communities. Although several AMP databases have been created and successfully exploited for AMP design, all of these use data collected on peptides tested against planktonic microorganisms. Here, an open-access, manually curated database of AMPs specifically assayed against microbial biofilms (BaAMPs) is presented for the first time. In collecting relevant data from the literature an effort was made to define a minimal standard set of essential information including, for each AMP, the microbial species and biofilm conditions against which it was tested, and the specific assay and peptide concentration used. The availability of these data in an organized framework will benefit anti-biofilm research and support the design of novel molecules active against biofilm. BaAMPs is accessible at http://www.baamps.it.

References

Feb 13, 2001·Trends in Microbiology·T F Mah, G A O'Toole
Apr 5, 2002·Clinical Microbiology Reviews·Rodney M Donlan, J William Costerton
Dec 31, 2005·Nucleic Acids Research·Cathy H WuBaris Suzek
Dec 13, 2006·Nature Biotechnology·Robert E W Hancock, Hans-Georg Sahl
Oct 30, 2008·Nucleic Acids Research·Guangshun WangZhe Wang
Apr 24, 2010·FEMS Immunology and Medical Microbiology·Iolanda Francolini, Gianfranco Donelli
Nov 9, 2010·Acta Biomaterialia·Fabíola CostaM Cristina L Martins
Nov 30, 2010·Current Medicinal Chemistry·Giovanna BatoniMario Campa
Nov 24, 2011·Nucleic Acids Research·Vijayaraghava Seshadri SundararajanVladimir B Bajic
Dec 17, 2011·Nature Reviews. Drug Discovery·Christopher D FjellGisbert Schneider
Feb 14, 2012·International Journal of Antimicrobial Agents·Stefano P PiottoPio Iannelli
Apr 3, 2012·Bioinformatics·Mario NovkovićDavor Juretić
Jul 5, 2013·PloS One·Xiaowei ZhaoQingshan Huang
Sep 17, 2013·PLoS Computational Biology·Giuseppe MaccariAngelo Bifone
Nov 23, 2013·Nucleic Acids Research·Faiza Hanif WaghuSusan Idicula-Thomas

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Citations

Nov 4, 2015·Nucleic Acids Research·Sandeep SinghGajendra P S Raghava
Jan 29, 2016·ACS Medicinal Chemistry Letters·Biswajit MishraGuangshun Wang
Nov 4, 2015·Biochimica Et Biophysica Acta·Giovanna BatoniSemih Esin
Jan 3, 2016·Biochimica Et Biophysica Acta·César de la Fuente-NúñezRobert E W Hancock
May 18, 2016·Scientific Reports·Ankur GautamGajendra Pal Singh Raghava
Jul 6, 2016·Frontiers in Microbiology·Sudheer GuptaVineet K Sharma
Aug 10, 2016·Future Medicinal Chemistry·Tecla CiociolaLuciano Polonelli
Nov 22, 2016·Critical Reviews in Microbiology·Joana AzeredoClaus Sternberg
Feb 26, 2016·Scientific Reports·Arun SharmaAnshu Bhardwaj
Apr 14, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lisa LombardiArianna Tavanti
May 19, 2018·Biomolecules·Athina AndreaHåvard Jenssen
Aug 5, 2018·Journal of Cellular Biochemistry·Samira JahangiriFaramarz Mehrnejad
Feb 1, 2018·Scientific Reports·Evan F HaneyRobert E W Hancock
May 10, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jiajia HongKai Yang
Nov 20, 2019·Life Science Alliance·Francisco Ramos-MartínNicola D'Amelio
Jul 24, 2015·Biomolecular Concepts·Małgorzata Cytryńska, Agnieszka Zdybicka-Barabas
Mar 19, 2020·Current Pharmaceutical Design·Kleber Santiago SilvaMaristela Pereira
Apr 11, 2017·Frontiers in Microbiology·Juliana M AnsariErol Fikrig
Oct 31, 2019·BioMed Research International·Edward Ntim GasuLawrence Sheringham Borquaye
Oct 4, 2017·Frontiers in Chemistry·Martijn RioolSebastian A J Zaat
Feb 12, 2020·Scientific Reports·Durdam DasShailesh Kumar
Feb 20, 2019·Frontiers in Chemistry·Evan F HaneyRobert E W Hancock
Sep 29, 2019·Toxins·Elias Ferreira Sabiá JúniorElisabeth Ferroni Schwartz
Jan 30, 2018·Frontiers in Microbiology·Lucia GrassiGiovanna Batoni
Feb 5, 2021·ACS Nano·Marcelo D T TorresCesar de la Fuente-Nunez
Jan 10, 2021·International Journal of Molecular Sciences·Giovanna BatoniSemih Esin
Jan 30, 2021·Biofouling·Fábio G MartinsSérgio F Sousa
Feb 18, 2021·Cellular and Molecular Life Sciences : CMLS·M D MannielloP Falabella
Jan 7, 2019·Journal of Molecular Biology·Marcelo D T TorresCesar de la Fuente-Nunez

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Software Mentioned

PubMed
BaAMPs
BLASTP
Scopus
MySQL
Joomla
BLAST

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