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Bacitracin inhibits fibronectin matrix assembly by mesangial cells in high glucose

Kidney International

Nov 13, 2001

B S WestonR M Mason

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Abstract

Accumulation of mesangial extracellular matrix is a major characteristic of diabetic nephropathy (DN). Expression of several extracellular matrix proteins is up-regulated in human mesangial cells (HMC) cultured in high glucose. One protein, fibronectin (FN), associates to form an insolu...read more

Mentioned in this Paper

RNase Activity
Buffers
Bacitracin
Polyvinylidene fluoride
Deoxyribonuclease I
Diabetic Nephropathy
Scintillation Counting
2-Mercaptoethanol
Western Blotting
SDS-PAGE
13
1
Paper Details
References
  • References46
  • Citations7
12345
  • References46
  • Citations7

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Bacitracin inhibits fibronectin matrix assembly by mesangial cells in high glucose

Kidney International

Nov 13, 2001

B S WestonR M Mason

PMID: 11703593

DOI: 10.1046/j.1523-1755.2001.00991.x

Abstract

Accumulation of mesangial extracellular matrix is a major characteristic of diabetic nephropathy (DN). Expression of several extracellular matrix proteins is up-regulated in human mesangial cells (HMC) cultured in high glucose. One protein, fibronectin (FN), associates to form an insolu...read more

Mentioned in this Paper

RNase Activity
Buffers
Bacitracin
Polyvinylidene fluoride
Deoxyribonuclease I
Diabetic Nephropathy
Scintillation Counting
2-Mercaptoethanol
Western Blotting
SDS-PAGE
13
1

Feeds With Similar Papers

Mitochondria & Diabetic Nephropathy

Mitochondria can sense ecm composition changes, and changes in mitochondrial functioning modify the ecm. Discover the latest research on how mitochondrial changes affect diabetic nephropathy.

Integrin Signalling

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion. Upon ligand binding, integrins activate signal transduction pathways that mediate cellular signals such as regulation of the cell cycle, organization of the intracellular cytoskeleton, and movement of new receptors to the cell membrane. Discover the latest research on integrin signalling here.

Related Papers

Paper Details
References
  • References46
  • Citations7
12345
  • References46
  • Citations7

Download from

Publisher
PubMed
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