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Background selection as null hypothesis in population genomics: insights and challenges from Drosophila studies

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Nov 8, 2017

Josep M Comeron

Abstract

The consequences of selection at linked sites are multiple and widespread across the genomes of most species. Here, I first review the main concepts behind models of selection and linkage in recombining genomes, present the difficulty in parametrizing these models simply as a reduction ...read more

Mentioned in this Paper

Study
Size
Genome
Genes
Genetics, Population
Recombination, Genetic
Drosophila
Equilibrium
Baller-Gerold Syndrome
Site
62
86
Paper Details
References
  • References129
  • Citations13
12345...
  • References129
  • Citations13
12

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Background selection as null hypothesis in population genomics: insights and challenges from Drosophila studies

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Nov 8, 2017

Josep M Comeron

PMID: 29109230

DOI: 10.1098/rstb.2016.0471

Abstract

The consequences of selection at linked sites are multiple and widespread across the genomes of most species. Here, I first review the main concepts behind models of selection and linkage in recombining genomes, present the difficulty in parametrizing these models simply as a reduction ...read more

Mentioned in this Paper

Study
Size
Genome
Genes
Genetics, Population
Recombination, Genetic
Drosophila
Equilibrium
Baller-Gerold Syndrome
Site
62
86

Feeds With Similar Papers

Parasite Genetics

Parasite genetics is the study of the genetic material of parasites. Here is the latest research on parasite genetics.

Gene Evolution & Mutation

The identification of precise mutations is required for a complete understanding of the underlying molecular and evolutionary mechanisms driving adaptive phenotypic chang

Related Papers

Briefings in Functional Genomics

The impact of linked selection on plant genomic variation

Briefings in Functional GenomicsApril 25, 2014
Tanja Slotte
Paper Details
References
  • References129
  • Citations13
12345...
  • References129
  • Citations13
12

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