PMID: 3745131Sep 1, 1986Paper

Baclofen treatment in a patient with tardive dystonia

The Journal of Clinical Psychiatry
R B RosseW E Lux

Abstract

The use of baclofen, a structural analog of gamma-aminobutyric acid (GABA), is described in the treatment of a patient with tardive dystonia. The patient, a woman with a clinical diagnosis of Alzheimer's disease, developed tardive dystonia after 8 weeks of haloperidol therapy and experienced complete remission of her dystonia while taking baclofen 60 mg/day. This case suggests that baclofen may facilitate remission of tardive dystonia in some cases and provides a basis for further investigation.

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