Bacteremia Caused by Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae in Vientiane, Lao PDR: A 5-Year Study

The American Journal of Tropical Medicine and Hygiene
Ko ChangDavid A B Dance

Abstract

Although there has been an increasing incidence of bacteremia caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) across South East Asia, there are sparse data from the Lao PDR, where laboratory capacity for antimicrobial resistance surveillance is limited. We, therefore, retrospectively reviewed bacteremia caused by ESBL-producing Escherichia coli and Klebsiella pneumoniae between 2010 and 2014 at Mahosot Hospital, Vientiane, Lao PDR. Clinical and laboratory data relating to all episodes of ESBL-E bacteremia were reviewed over the 5-year period and compared with non-ESBL-E bacteremia. Blood cultures positive for E. coli or K. pneumoniae were identified retrospectively from laboratory records. Clinical and laboratory data were extracted from research databases and case notes and analyzed using STATA. Between 2010 and 2014, we identified 360 patients with E. coli (n = 249) or K. pneumoniae (n = 111) bacteremia, representing 34.8% of all patients with clinically significant bacteremia. Seventy-two (20%) isolates produced ESBL; E. coli accounted for 15.3% (55/360) and K. pneumoniae for 4.7% (17/360), respectively. The incidence of ESBL-producing E. coli bacteremia rose during the study period. B...Continue Reading

References

Apr 3, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E LautenbachN O Fishman
Jul 13, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·L RomeroA Pascual
Mar 30, 2006·Antimicrobial Agents and Chemotherapy·Mitchell J SchwaberYehuda Carmeli
Jul 4, 2006·American Journal of Infection Control·David L Paterson
Nov 17, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J Rodríguez-BañoA Pascual
Sep 10, 2009·Revista Do Instituto De Medicina Tropical De São Paulo·Silvana Vargas SupertiAlexandre Prehn Zavascki
Aug 7, 2010·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Un-In WuShan-Chwen Chang
Aug 24, 2011·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Olivia Ferrández QuiranteSonia Luque Pardos
Oct 12, 2011·The Journal of Antimicrobial Chemotherapy·Nicole StoesserNicola Jones
Feb 13, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·K B Laupland
Aug 24, 2013·The Lancet Infectious Diseases·L Silvia Munoz-PriceJohn P Quinn
Oct 4, 2014·Clinical Microbiology Reviews·Kevin B Laupland, Deirdre L Church
Feb 27, 2015·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E R VliegheY Glupczynski
Aug 1, 2015·Bulletin of the World Health Organization·Fabrice QuetJan Jacobs
Mar 13, 2016·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Hazuki NakaiHiroshige Mikamo
May 6, 2016·Antimicrobial Resistance and Infection Control·Nuntra Suwantarat, Karen C Carroll
Nov 2, 2016·Journal of Infection in Developing Countries·Samba Adama SangareIbrahim Izetiegouma Maiga
Dec 26, 2017·The Lancet Infectious Diseases·Evelina TacconelliUNKNOWN WHO Pathogens Priority List Working Group
Apr 6, 2018·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Oded ScheuermanUNKNOWN REIPI/ESGBIS/INCREMENT investigators

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

Excel
STATA

Related Concepts

Related Feeds

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.