PMID: 8604171Jan 17, 1996Paper

Bacteremia with Streptococcus pneumoniae. Implications for therapy and prevention. Franklin County Pneumonia Study Group

JAMA : the Journal of the American Medical Association
J F PlouffeR R Facklam

Abstract

To determine the incidence and mortality rates of patients with bacteremic infections with Streptococcus pneumoniae, and to determine the serotypes and antimicrobial susceptibilities of the pneumococcal isolates. Prospective case ascertainment and procurement of S pneumoniae isolates between January 1991 and April 1994. Ten adult care hospitals in Franklin County, Ohio. Patients (N = 590) in whom S pneumoniae was isolated from blood cultures. Demographic data from patients with pneumococcal bacteremia were obtained by chart review. Pneumococcal serotyping and antimicrobial susceptibility testing were performed on 499 bacteremic isolates. Among residents of Franklin County, the annual incidence of pneumococcal bacteremia was higher in patients at least 65 years old (83.0 per 100,000 population) compared with younger adults (9.6 per 100,000 population) (odds ratio [OR], 8.74; 95% confidence interval [CI], 7.19 to 10.62) and more common among African Americans than whites (OR, 1.36; 95% CI, 1.06 to 1.75). The relative risk of pneumococcal bacteremia among persons infected with the human immunodeficiency virus was 41.8 times (CI, 19.0 to 92.0) that of county residents 18 to 64 years of age. The overall mortality rate was 19% and wa...Continue Reading

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Citations

Aug 12, 2014·Semergen·F Casas MaldonadoD A Vargas Ortega
Oct 1, 1996·Emerging Infectious Diseases·M A Winker
Jul 1, 1997·Journal of Accident & Emergency Medicine·A R WassJ I Wilson
Apr 15, 2003·Clinical Microbiology Reviews·Andrew S ArtzDan L Longo
Jul 2, 2004·BMC Infectious Diseases·Pernille MartensThomas Benfield
Apr 29, 2006·BMC Infectious Diseases·Galo PeraltaMaría Pía Roiz
Jun 16, 2009·Immunity & Ageing : I & a·Hajo Haase, Lothar Rink
Oct 22, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·W KrzyściakD Kościelniak
Oct 1, 2005·Tijdschrift voor gerontologie en geriatrie·T Carels, J Flamaing
Dec 29, 2000·Comprehensive Therapy·M Gotfried, C Freeman
Aug 1, 1997·Journal of Paediatrics and Child Health·K GrimwoodP B McIntyre
Apr 26, 2002·British Journal of Haematology·Dan EngelhardUNKNOWN Infectious Disease Working Party of the European Bone Marrow Transplantation (IDWP-EBMT)
Nov 30, 2000·Current Infectious Disease Reports·P RochaA R Tunkel
Feb 15, 2001·Current Infectious Disease Reports·Lionel A. Mandell
May 23, 2003·Current Infectious Disease Reports·Michael Henry, Howard L. Leaf
May 15, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J S ChristensenA Lassen
Oct 5, 2002·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·L K SiuChih-Chien Wang
Jul 1, 1997·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·J C Butler
Mar 9, 2000·The New England Journal of Medicine·J V Sheffield, R K Root
Mar 28, 1996·The New England Journal of Medicine·L A Mandell, M S Niederman
Mar 9, 2000·The New England Journal of Medicine·J P NuortiR F Breiman
May 20, 2005·The New England Journal of Medicine·Thomas R TalbotMarie R Griffin
Sep 21, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M I Neuman, M B Harper
Jul 31, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A S KarstaedtH H Crewe-Brown
Oct 26, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·T J Marrie
Jul 30, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Julia Y MoritaCynthia G Whitney
Aug 31, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joan-Josep CanetJavier Garau
Jan 23, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John J RossDaniel S Shapiro
Mar 5, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Javier AspaUNKNOWN Pneumococcal Pneumonia in Spain Study Group
Feb 19, 2002·International Journal of Antimicrobial Agents·Helena K Parsons, David H Dockrell
Jul 3, 2013·The Medical Clinics of North America·Samuel Y Ash, John V L Sheffield
Mar 27, 2012·Médecine et maladies infectieuses·J Obert, P-R Burgel
Sep 16, 2011·Vaccine·Ana Lucia AndradeJoão Guimarães Andrade
May 4, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·T M File
Nov 3, 2007·The Lancet Infectious Diseases·Sandra J BlissOrin S Levine

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