PMID: 3881449Feb 1, 1985Paper

Bacterial adherence to biomaterials and tissue. The significance of its role in clinical sepsis

The Journal of Bone and Joint Surgery. American Volume
A G Gristina, J W Costerton

Abstract

The direct examination of tissue and biomaterials from prosthesis-related infections of twenty-five patients showed that the causative bacteria grew in glycocalyx-enclosed biofilms that were adherent to surfaces of biomaterials and tissues in 76 per cent. This high rate of recovery of adherent biofilm-mediated growth suggests that the process occurs commonly in the presence of a foreign body or biomaterial-related infection. Because of the adherent mode of growth of the infecting organisms, accurate microbiological sampling was difficult. The analysis of joint fluids or of swabs of excised tissue and of prosthetic surfaces often yielded only one species from what was a polymicrobial population based on electron microscopic studies. We adapted direct quantitative sampling methods from environmental microbiology in order to recover a large number of species from these infections, but comparison of the organisms isolated by these techniques with the morphological types that were seen by electron microscopy indicated that in some instances all bacterial components of the biofilms were still not being recovered.

Citations

May 17, 2003·International Orthopaedics·J C De Lucas-VillarrubiaE Gomez-Barrena
Aug 10, 2006·International Orthopaedics·Imran RafiqP R Kay
Mar 20, 2009·International Orthopaedics·Muhittin SenerAsli Gamze Karataş Sener
Apr 21, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Mario Di SilvestreStefano Giacomini
Feb 16, 2013·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Ke LiuYong-Qiang Zhao
Nov 1, 1987·Biomaterials·A G GristinaQ N Myrvik
Oct 31, 2003·Biomaterials·J G E HendriksH J Busscher
Nov 1, 2003·The Spine Journal : Official Journal of the North American Spine Society·Bikash Bose
Jun 23, 2010·Seminars in Plastic Surgery·Paul DinhMilan V Stevanovic
Jun 1, 1993·Antimicrobial Agents and Chemotherapy·M DrancourtD Raoult
Jan 2, 2014·TheScientificWorldJournal·Maximilian HaenleRainer Bader
Aug 5, 2008·The Journal of Bone and Joint Surgery. American Volume·Paul StoodleySandeep Kathju
May 14, 2010·International Journal of Nanomedicine·Liao JuanZhang Jingchao
Apr 24, 2013·Journal of Visualized Experiments : JoVE·Hongshuai Li, Bingyun Li
Jan 27, 2006·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Seisuke NishimuraHiroyuki Shindo
Mar 10, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Mian ChenLan Zhang
Mar 1, 1994·Journal of Cataract and Refractive Surgery·C R ArciolaA Pizzoferrato
Jun 1, 1991·The Journal of Arthroplasty·K DavenportC Perry
Feb 11, 2014·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Keishi Maruo, Sigurd H Berven
Jan 1, 1988·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·G J NishiokaT B Aufdemorte
Jun 7, 2008·The Journal of Arthroplasty·Georg GoshegerChristof von Eiff
Nov 27, 2004·The Laryngoscope·Bryan M DavisDavid S Haynes
Jun 9, 2009·The Laryngoscope·Donald H SolomonAhmed M S Soliman
Jun 10, 2009·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Toshiharu ShiraiKatsuro Tomita
Nov 10, 2012·Journal of Biomedical Materials Research. Part a·Abbas Ali Imani FooladiMohammad Reza Nourani
Oct 20, 2010·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Dan HøgdallLise Christensen
Nov 3, 2010·Clinical Oral Implants Research·Olivia Pons-VicenteCosme Gay-Escoda
Aug 21, 2010·Journal of Biomedical Materials Research. Part a·Xiang GeFuzeng Ren
Dec 10, 1991·Clinical Materials·E F DiCarlo, P G Bullough
Jun 5, 2010·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Poroshat KhalilpourVolker Alt
Jun 27, 2009·Journal of Biomedical Materials Research. Part a·Richard A SmithNadim James Hallab

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