PMID: 21365044Mar 3, 2011

Bacterial adhesion and colonization differences between zirconium oxide and titanium alloys: an in vivo human study

The International Journal of Oral & Maxillofacial Implants
Umut SalihogluKoksal Balos


The purpose of this study was to compare zirconium oxide and titanium alloys with respect to their tendency to adhesion and colonization of two periodontal pathogens on both hard surfaces and on soft tissues in vivo. The present study was designed as a prospective stratified randomized controlled clinical trial. Patients were scheduled to receive two implants with different types of abutments in the posterior mandible. Three months after implant placement, titanium and zirconium abutments were connected. Five weeks after abutment connections, the abutments were removed, probing depth measurements were recorded, and gingival biopsy samples were obtained. Abutments and biopsy specimens were analyzed by reverse-transcriptase polymerase chain reaction to compare the DNA copy numbers of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, and total bacteria. The surface free energy of the abutments was calculated by sesile water drop before replacement. No statistically significant differences were found between probing depths or DNA copy numbers of A actinomycetemcomitans, P gingivalis, and total bacteria both for both titanium alloys and zirconium oxide surfaces and the biops specimens obtained from their buccal gingiv...Continue Reading

Related Concepts

Zirconium oxide, (95)Zr-labeled
Dental Abutments
Bacterial Adhesion
Dental Alloys
Dental Materials
DNA, Bacterial
Interdental Papilla
Jaw, Edentulous, Partially
Mylohyoid Ridge

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