Bacterial chemolithoautotrophy via manganese oxidation.

Nature
Hang Yu, Jared R Leadbetter

Abstract

Manganese is one of the most abundant elements on Earth. The oxidation of manganese has long been theorized1-yet has not been demonstrated2-4-to fuel the growth of chemolithoautotrophic microorganisms. Here we refine an enrichment culture that exhibits exponential growth dependent on Mn(II) oxidation to a co-culture of two microbial species. Oxidation required viable bacteria at permissive temperatures, which resulted in the generation of small nodules of manganese oxide with which the cells associated. The majority member of the culture-which we designate 'Candidatus Manganitrophus noduliformans'-is affiliated to the phylum Nitrospirae (also known as Nitrospirota), but is distantly related to known species of Nitrospira and Leptospirillum. We isolated the minority member, a betaproteobacterium that does not oxidize Mn(II) alone, and designate it Ramlibacter lithotrophicus. Stable-isotope probing revealed 13CO2 fixation into cellular biomass that was dependent upon Mn(II) oxidation. Transcriptomic analysis revealed candidate pathways for coupling extracellular manganese oxidation to aerobic energy conservation and autotrophic CO2 fixation. These findings expand the known diversity of inorganic metabolisms that support life, and...Continue Reading

References

Mar 1, 1977·Bacteriological Reviews·R K ThauerK Decker
Dec 24, 1997·Applied and Environmental Microbiology·D Emerson, C Moyer
Aug 10, 1999·Nature·M StrousM S Jetten
Oct 31, 2000·Applied and Environmental Microbiology·M T SuzukiE F DeLong
Nov 28, 2000·Journal of Bacteriology·J R Leadbetter, E P Greenberg
Feb 27, 2004·Nucleic Acids Research·Wolfgang LudwigKarl-Heinz Schleifer
Jun 25, 2004·Nucleic Acids Research·Pantelis G BagosStavros J Hamodrakas
Nov 3, 2004·Advances in Microbial Physiology·Derek R LovleyKelly P Nevin
Apr 12, 2005·Environmental Microbiology·Abraham Esteve-NúñezDerek Lovley
Aug 2, 2005·Trends in Microbiology·Bradley M TeboAlexis S Templeton
Sep 24, 2005·Nature·Martin KönnekeDavid A Stahl
Nov 5, 2005·Applied and Environmental Microbiology·Birgit E M KanzlerJörg Overmann
Nov 1, 1994·Applied and Environmental Microbiology·D Emerson, N P Revsbech
Jan 21, 2006·Environmental Microbiology·Holger DaimsMichael Wagner
Feb 16, 2006·Environmental Microbiology·Suvi F Flagan, Jared R Leadbetter
Dec 26, 2006·Journal of Bacteriology·Yongqin Jiao, Dianne K Newman
Mar 18, 2008·Applied and Environmental Microbiology·Gregory J DickBradley M Tebo
Apr 13, 2010·Nature Methods·J Gregory CaporasoRob Knight
Jul 14, 2010·Proceedings of the National Academy of Sciences of the United States of America·Sebastian LückerHolger Daims
Aug 17, 2010·Bioinformatics·Robert C Edgar
Jan 11, 2011·Applied and Environmental Microbiology·Ivan A Berg
Oct 13, 2011·Molecular Systems Biology·Fabian SieversDesmond G Higgins
Dec 6, 2011·Nucleic Acids Research·Scott Federhen
Jan 10, 2012·Environmental Microbiology·Lubos PolereckyMarcel M M Kuypers
Feb 24, 2012·Systematic Biology·Fredrik RonquistJohn P Huelsenbeck
Mar 6, 2012·Nature Methods·Ben Langmead, Steven L Salzberg
Apr 18, 2012·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Anton BankevichPavel A Pevzner
May 5, 2012·Bioinformatics·Elmar PruesseFrank Oliver Glöckner
Jun 1, 2012·Molecular Microbiology·David J RichardsonThomas A Clarke
Oct 17, 2012·Bioinformatics·Evguenia KopylovaHélène Touzet
Nov 30, 2012·Nucleic Acids Research·Christian QuastFrank Oliver Glöckner

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Citations

Jul 3, 2020·Environmental Microbiology Reports·Nadia SzeinbaumJennifer B Glass
Jul 22, 2020·Nature Reviews. Microbiology·Ashley York
Oct 20, 2020·Environmental Microbiology Reports·J Cameron Thrash
Aug 21, 2020·FEMS Microbiology Ecology·Susanne SjöbergChristophe Dupraz
Jan 17, 2021·Microbial Ecology·Natascha Menezes BergoVivian Helena Pellizari
Dec 2, 2020·The Science of the Total Environment·Laura NewsomeJonathan R Lloyd
Oct 27, 2020·IScience·Patrick JungPeter Leinweber
Oct 24, 2020·Nature Reviews. Microbiology·William H LewisThijs J G Ettema
Apr 17, 2021·Journal of Hazardous Materials·Pengfei SunJan Dolfing
May 27, 2021·FEMS Microbiology Reviews·Elleke F BosmaSolvej Siedler
Jun 29, 2021·Frontiers in Microbiology·Douglas E LaRoweJan P Amend
Jun 24, 2021·FEMS Microbiology Ecology·Maureen A O'Malley, David A Walsh
Sep 2, 2021·Environmental Science & Technology·Hui LiElizabeth Herndon
Sep 25, 2021·Environmental Science & Technology·Yanchen SunFrank E Löffler
Sep 26, 2021·Plant, Cell & Environment·Jana MittelstrassMatthew W Horton

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Methods Mentioned

BETA
infrared spectroscopy
Fluorescence
Assay
light microscopy
scanning electron microscopy
PCR
restriction

Software Mentioned

CheckM
MrBayes
mmgenome
BBMap
kallisto 93
fastq
RAxML
GTDB
TMBB
sortmerna

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