PMID: 7034965Nov 1, 1981Paper

Bacterial chemotaxis in the absence of receptor carboxylmethylation

Cell
J B StockD E Koshland

Abstract

Although chemoreceptor methylation in Salmonella typhimurium and Escherichia coli has been shown to be at the core of the chemotactic phenomenon, mutants in the gene (cheR) that codes for the methylating enzyme still respond and adapt to repellent stimuli. Analyses of receptor methylation and transferase activity show that this behavior is not due to residual transferase activity. That receptor methylation is not absolutely required for chemotactic sensory processing is confirmed by the isolation of cheR pseudorevertants that remain defective in receptor methylation, yet are able to respond to gradients on semi-solid tryptone agar. A detailed comparison of cheR and wild-type responses indicates that chemotaxis is mediated by at least two interdependent adaptation systems, only one of which involves receptor methylation. The interaction of these two systems produces the full response in wild-type cells. Methylation-deficient mutants exhibit a partial response and retain some chemotactic ability.

Citations

Jun 15, 1984·Journal of Molecular Biology·H BöckT Igo-Kemenes
Jan 1, 1987·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·A van Waarde
Jun 1, 1994·Research in Microbiology·P B CarpenterG W Ordal
Jun 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M R KehryF W Dahlquist
Aug 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·E Bogonez, D E Koshland
Dec 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J StockJ E Burchenal
Jan 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·R M Weis, D E Koshland
Mar 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·G L HazelbauerD M Nowlin
Aug 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·K A BorkovichM I Simon
Jun 22, 2006·Journal of Bacteriology·Bonnie B StephensGladys Alexandre
Nov 22, 2001·Journal of Bacteriology·A C MartinJ P Armitage
Jun 4, 2004·Journal of Bacteriology·Sergei I BibikovJohn S Parkinson
Jun 10, 2004·Microbiology and Molecular Biology Reviews : MMBR·Hendrik Szurmant, George W Ordal
Dec 21, 2011·Canadian Journal of Microbiology·Cindy R Deloney-Marino, Karen L Visick
Aug 9, 1988·Biochemistry·D E Koshland
May 26, 2017·FEBS Letters·Szilvia Baron, Michael Eisenbach
Aug 26, 2006·Nature Clinical Practice. Endocrinology & Metabolism·Annamaria ColaoGaetano Lombardi
Jan 26, 2006·Experimental Dermatology·Sylvie Verdier-SévrainBarbara Gilchrest
Dec 5, 1998·Journal of Molecular Biology·Y BlatM Eisenbach
Dec 1, 1989·Microbiological Reviews·J B StockA M Stock
Dec 1, 1988·Journal of Bacteriology·P S Poole, J P Armitage
Oct 1, 1982·Journal of Bacteriology·J L SlonczewskiA M Castle
Sep 1, 1985·Microbiological Reviews·P W Postma, J W Lengeler

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