PMID: 7992606Jan 1, 1994Paper

Bacterial contamination of allografts

Acta orthopaedica Belgica
R H BarriosC Oteiza

Abstract

The risk of bacterial infection through allogeneic bone transplantation is one of the problems facing tissue banks. The purpose of this study is to report the contamination rate in 987 grafts obtained under strictly aseptic conditions, between 1989 and 1992. The grafts were stored at -80 degrees C (cortical bone and tendons) and -40 degrees C (cancellous bone). The overall contamination rate was 6.6%, with Gram-positive bacteria responsible for 80% of the positive cultures. We discuss the sources of contamination, the most frequently isolated bacteria and the steps in the donation and transplantation procedures that help to reduce the risk of contamination. We conclude that the methods of procurement, processing and storage of tissues are effective in making sterile allografts available.

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Related Papers

Acta orthopaedica Belgica
R H BarriosC Oteiza
Zhonghua wai ke za zhi [Chinese journal of surgery]
J Zhang
The Journal of Nursing Administration
M M Wake
The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
D J ChambersD J Hearse
© 2021 Meta ULC. All rights reserved