Bacterial counts in cerebrospinal fluid of children with meningitis

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
E BingenH Mathieu

Abstract

Eighty-five cerebrospinal fluid (CSF) specimens from the same number of pediatric patients with meningitis were examined to determine the bacterial count and the relationship of this count to the microscopy results, the ages of the patients and the bacterial species isolated. Bacterial counts ranged from 2 x 10 to 4 x 10(9) CFU/ml CSF. Twenty-five percent of the 85 CSF specimens positive for Haemophilus influenzae type b, Neisseria meningitidis, Streptococcus pneumoniae, Escherichia coli K1 and group B streptococci had counts of 10(7) CFU/ml or higher. Children between 1 and 6 months of age had significantly higher counts (p less than 0.05) than the other age groups. The three patients who had positive CSF cultures 24 h after the start of therapy all had initial bacterial counts of 10(7) CFU/ml or higher. The detection limit for Gram stain/microscopy was 10(5) CFU/ml. No correlation was found between bacterial count and the number of polymorphonuclear leukocytes.

References

Oct 1, 1979·Antimicrobial Agents and Chemotherapy·V P SyriopoulouA L Smith
Oct 1, 1989·The Journal of Infectious Diseases·D L Hatch, G D Overturf
Aug 1, 1983·Antimicrobial Agents and Chemotherapy·C LaferriereD F Welch

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Citations

Jan 1, 1992·Diagnostic Cytopathology·A E Walts
Dec 1, 1994·Diagnostic Microbiology and Infectious Disease·L R FriedlandD J Hassett
Aug 29, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·X Zhao, K Drlica
Jan 1, 1995·Antimicrobial Agents and Chemotherapy·J L GaillardC Coustere
Feb 13, 2001·Antimicrobial Agents and Chemotherapy·J M BlondeauK Drlica
Apr 16, 2004·Clinical Microbiology Reviews·Douglas A DrevetsRonald A Greenfield
May 17, 2011·PloS One·Jennifer Dolan ThomasLeonard W Mayer
Jul 16, 2008·Clinical Chemistry and Laboratory Medicine : CCLM·Mariam Klouche, Uwe Schröder
Dec 19, 2015·Journal of Veterinary Internal Medicine·A G BoyleH Wheeler-Aceto
May 9, 2012·Veterinary Microbiology·Ashley G BoyleShelley C Rankin
Feb 5, 2010·The Lancet Infectious Diseases·Kwang Sik Kim
Mar 14, 2009·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·E Georget-BouquinetUNKNOWN Groupe des Pédiatres et Microbiologistes de l'Observatoire National des Méningites Bactériennes de l'Enfant
Nov 8, 2008·Diagnostic Microbiology and Infectious Disease·Irmeli RoineUNKNOWN LatAm Meningitis Study Group
Mar 1, 1997·The Journal of Urology·R E BergerS L Hillier
May 25, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D I Andersson
May 25, 2004·Expert Opinion on Pharmacotherapy·Joseph M Blondeau, Bayan Missaghi
Nov 5, 1999·Microbial Pathogenesis·B J MohammedC O'Callaghan
Sep 8, 2016·IEEE Journal of Translational Engineering in Health and Medicine·Akilan PalanisamiTayyaba Hasan
May 12, 2009·Médecine et maladies infectieuses·P Chavanet
Sep 2, 2004·The Annals of Pharmacotherapy·Benjamin J EpsteinKarl Drlica
Apr 4, 2008·FEMS Immunology and Medical Microbiology·Thomas A Russo, Ulrike Carlino-MacDonald
May 19, 2009·Expert Opinion on Pharmacotherapy·Kwang Sik Kim
Jul 13, 2017·Annual Review of Microbiology·Diarmaid Hughes, Dan I Andersson
May 3, 2020·Journal of Neuroinflammation·M Brittany JohnsonIan Marriott
Mar 4, 2019·Journal of Neuroinflammation·Amanda R BurmeisterIan Marriott
Jul 2, 1999·Antimicrobial Agents and Chemotherapy·I LutsarG H McCracken
May 23, 2021·Proceedings of the National Academy of Sciences of the United States of America·Maria Rosa LoffredoLorenzo Stella

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