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Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells

bioRxiv

Mar 4, 2015

Alain PacisLuis B. Barreiro

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Abstract

DNA methylation is thought to be robust to environmental perturbations on a short time scale. Here, we challenge that view by demonstrating that the infection of human dendritic cells (DCs) with a pathogenic bacteria is associated with rapid changes in methylation at thousands of loci. ...read more

Mentioned in this Paper

Landscapes
Study of Epigenetics
Cross Reactions
Intercellular Communication Process
Protein Demethylation
Dendritic Cells
Adaptive Immunity
Genetic Loci
Genes
Bacterial Infections
4
3
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  • Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells

    bioRxiv

    Mar 4, 2015

    Alain PacisLuis B. Barreiro

    PMID: 990016022

    DOI: 10.1101/016022

    Abstract

    DNA methylation is thought to be robust to environmental perturbations on a short time scale. Here, we challenge that view by demonstrating that the infection of human dendritic cells (DCs) with a pathogenic bacteria is associated with rapid changes in methylation at thousands of loci. ...read more

    Mentioned in this Paper

    Landscapes
    Study of Epigenetics
    Cross Reactions
    Intercellular Communication Process
    Protein Demethylation
    4
    3

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