Bacterial infections in pediatric patients during early post liver transplant period: A prospective study in Iran

Transplant Infectious Disease : an Official Journal of the Transplantation Society
Gholamreza PouladfarLeila Khosravifard

Abstract

Bacterial infection in early period after liver transplant (LT) is the main cause of morbidity and mortality; however, data on children is limited. To investigate the frequency, characteristics, and the associated factors of bacterial infection during hospitalization after LT, we prospectively enrolled all consecutive children with LT for a one-year, case-control study at the unique referral center of pediatric LT in Iran. Eighty-five events of bacterial infection were detected among 51 out of 94 LT recipients (54.3%) (infection group). Forty-three patients without bacterial infection constituted the control group. The frequency of bacterial infection based on the 51 microbiologically documented events was 31.9% (30 out of 94 patients). Major site of bacterial isolation were abdomen (43.6%). The following variables were associated with bacterial infection in univariate analysis: younger age (5.6 vs 8.9 years old), longer duration of JP Drain (13.4 vs 6.3 days), central venous catheter (14.6 vs 7.6 days), and Foley catheter insertion (7.3 vs 4.5 days), reoperation (57% vs 12% of patients), mean frequency of reoperation (1.1 vs 0.1 times), and intensive care unit stay (12.1 vs 6.5 days). In multivariate analysis, only longer hosp...Continue Reading

References

May 1, 1991·Reviews of Infectious Diseases·D L GeorgeC E Broelsch
Jun 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P M ArnowM E Irwin
Jan 1, 1997·Clinical Microbiology Reviews·R Patel, C V Paya
Oct 31, 1997·American Journal of Infection Control·N Singh
Jan 29, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·N SinghI R Marino
Nov 18, 2000·Pediatric Transplantation·R GanschowM Burdelski
Jan 11, 2001·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·N SinghI R Marino
Apr 12, 2003·Critical Care Medicine·Mitchell M LevyUNKNOWN SCCM/ESICM/ACCP/ATS/SIS
Apr 28, 2004·Transplantation Proceedings·B Sanromán BudiñoJ Mosquera Reboredo
Dec 21, 2007·The New England Journal of Medicine·Jay A Fishman
Dec 29, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·R W ShepherdUNKNOWN SPLIT Research Group
Feb 23, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas M HootonUNKNOWN Infectious Diseases Society of America
Jul 29, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A-P MagiorakosD L Monnet
Apr 10, 2012·Best Practice & Research. Clinical Gastroenterology·Bart van HoekHein W Verspaget
May 9, 2012·World Journal of Gastroenterology : WJG·Chuan LiBo Li
May 27, 2014·Clinics·Uenis Tannuri, Ana Cristina Aoun Tannuri
Oct 21, 2014·Critical Care Research and Practice·Vinay KukretiAlik Kornecki
Jun 30, 2015·The Pediatric Infectious Disease Journal·Kensuke ShojiAkihiko Saitoh
Sep 13, 2015·Pediatric Transplantation·Alexandra DreyzinGeorge V Mazariegos
Jun 1, 2012·Journal of the Pediatric Infectious Diseases Society·Michael Green, Marian G Michaels
Mar 19, 2016·Transplant Infectious Disease : an Official Journal of the Transplantation Society·L Ashkenazi-HoffnungJ Amir
May 27, 2016·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Jonathan Hand, Gopi Patel

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Citations

Jun 23, 2020·Transplantation·Hanifah OswariSastiono Soedibyo
Dec 1, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Laura L BioHayley A Gans
May 7, 2021·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Ming MaWentao Jiang

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