PMID: 6397450Jan 1, 1984Paper

Bacterial meningitis in infants and children

Infection
M I Marks

Abstract

Bacterial meningitis of infants and children exact a major toll worldwide. Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis continue to be the major causes, and efforts to reduce the incidence of this disease have had limited success. Major advances in rapid diagnosis, such as antigen detection, have occurred over the past several decades; however, Gram stain, cytologic examination and culture of the CSF remain the most reliable means of making an etiologic diagnosis. Despite shifts in bacterial susceptibilities to commonly used antibacterial agents, penicillin, ampicillin and chloramphenicol remain effective therapy for the vast majority of cases, although newer cephalosporin derivatives may be required to avoid the toxicities of chloramphenicol and to effectively treat selected bacteria that have developed resistance to these more classical antibiotics. The prognosis for bacterial meningitis in infants and children remains guarded because of late diagnosis and the severity of the disease. Major reductions in the incidence of the disease will depend on definition of high-risk populations and application of appropriate preventions.

References

Feb 1, 1979·American Journal of Diseases of Children·G A AhronheimM I Marks
Oct 1, 1979·Archives of Disease in Childhood·K D Connolly
Jan 1, 1978·The Journal of Pediatrics·E KolyvasC H Pai
Nov 1, 1978·The Journal of Pediatrics·A M LynnB H Ward
Aug 1, 1977·American Journal of Diseases of Children·R M Laxer, M I Marks
Aug 1, 1972·Clinical Pediatrics·J D MurrayM W Fujiwara
May 1, 1984·American Journal of Diseases of Children·V H San JoaquinM I Marks
Aug 1, 1983·Antimicrobial Agents and Chemotherapy·C LaferriereD F Welch
Mar 1, 1984·The Journal of Pediatrics·S A ChartrandD F Frederick
Dec 1, 1983·The Journal of Pediatrics·S A ChartrandR K Scribner
Oct 29, 1981·The New England Journal of Medicine·D W TeeleJ O Klein
Dec 1, 1981·The Journal of Pediatrics·E I TuomanenA L Smith
Sep 1, 1982·Infection·M I MarksL B Corbeil
Jul 1, 1981·European Journal of Pediatrics·L J Beard, Y H Thong
Jan 1, 1980·Infection·A S Prince, H C Neu

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Citations

May 1, 1987·Diagnostic Microbiology and Infectious Disease·G S BosleyR R Facklam
Apr 12, 2000·Journal of Paediatrics and Child Health·Y S LeeB W Lee
Sep 1, 1986·Zentralblatt Für Bakteriologie, Mikrobiologie, Und Hygiene. Series A, Medical Microbiology, Infectious Diseases, Virology, Parasitology·E A HeinemeyerN Temme
Jan 30, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·Cynthia L GongJoel W Hay
Apr 16, 2011·Epidemiology and Infection·A VyseM Soriano-Gabarro
Feb 1, 1995·Epidemiology and Infection·J S CheesbroughS D Green

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