Abstract
To delineate the epidemiologic trend, clinical characteristics and therapeutic outcomes of bacterial meningitis in young adults in Southern Taiwan. Over a period of 18 years, 329 cases of culture-proven adult bacterial meningitis were identified at our hospital. Among these 329 cases, 62 were identified as young adults (< or = 40 years) and their clinical features, laboratory data and therapeutic outcomes were reviewed. The prognostic factors between fatal and non-fatal groups were compared. The 62 young adults were 48 men and 14 women, aged 17-40 years. Thirty of the 62 patients belonged to nosocomial infection, and the other 32 belonged to community-acquired infection. A total of 74% (46/62) of the patients had a post-neurosurgical state as the underlying condition. Alcoholism (n = 8) was the most common underlying condition of the other 16 patients with spontaneous meningitis. Of these 62 patients, Klebsiella pneumoniae and Pseudomonas aeruginosa were the most common implicated gram-negative pathogens. During the late study period, there was an increase in coagulase-negative staphylococcus and Staphylococcus aureus infections. The therapeutic results of this group of patients are as follows: 13 patients died, 18 had full rec...Continue Reading
Citations
Apr 16, 2011·Epidemiology and Infection·A VyseM Soriano-Gabarro
Mar 15, 2012·The Journal of the Egyptian Public Health Association·Eman Ibrahim Mobarak
Apr 1, 2013·Acta Neuropsychiatrica·Tatiana BarichelloEmilio Streck
May 20, 2011·BMC Infectious Diseases·Chi-Ren HuangWen-Neng Chang
Jan 15, 2008·Infection·W-N ChangC-C Chien
Jan 5, 2014·Biomedical Journal·Wei-An LaiWen-Neng Chang
Nov 26, 2008·Diagnostic Microbiology and Infectious Disease·Athanasia XirogianniJenny Kourea-Kremastinou
Mar 18, 2008·Travel Medicine and Infectious Disease·Lucio BoglionePietro Caramello
Apr 9, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Emily HenkleMark G Thompson
Jul 10, 2013·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Maria de Fátima Magalhães Acioly MendizabalDemócrito de Barros Miranda-Filho
Feb 17, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Allan R TunkelJoseph R Zunt
Dec 31, 2016·World Neurosurgery·Roman MounierGilles Dhonneur
Jun 17, 2016·Microbiology and Molecular Biology Reviews : MMBR·Michelle K Paczosa, Joan Mecsas
Nov 16, 2016·Scientific Reports·Kiril E B van VeenDiederik van de Beek
Aug 9, 2017·BioMed Research International·Fahmi Yousef KhanDoiphode Sanjay
Jan 16, 2020·Intensive Care Medicine·Geert MeyfroidtRomain Sonneville
Apr 25, 2018·Journal of Medical Case Reports·Taro NoguchiSatoshi Ichiyama