Bacterial oxidation of 2-tridecanone to 1-undecanol.

Journal of Bacteriology
F W ForneyR E Kallio

Abstract

A study of the microbial utilization of long-chain methyl ketones was under-taken. In general, enrichment culture experiments revealed that soil microorganisms capable of utilizing these compounds as growth substrates are ubiquitous. Gram-negative, rod-shaped bacteria were the prominent organisms exhibiting this capability. In particular, a strain of Pseudomonas isolated from soil degraded 2-tridecanone into several products that were recovered from cell-free culture fluid. These products were identified by gas-liquid chromatography as 2-tridecanol, 1-undecanol, 1-decanol, and undecanoic acid. A large amount of the substrate was converted to 1-undecanol. This compound was characterized further by classical methods of organic analysis. Unequivocal identification of 1-undecanol has established that some unique mechanism that involves subterminal oxidation must exist to degrade 2-tridecanone. No such mechanism has been reported for the biological degradation of long-chain, aliphatic, methyl ketones. A pathway for utilization of 2-tridecanone was proposed that is consistent with, but not confirmed by, the data presented.

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Citations

Oct 14, 2014·AMB Express·Andy BeierFrieder Schauer
Jan 1, 1973·Antonie van Leeuwenhoek·G W Lijmbach, E Brinkhuis
Jul 1, 1971·Lipids·J E AllenA J Markovetz
Jan 1, 1968·Antonie van Leeuwenhoek·J J Perry
Apr 1, 1970·Journal of Bacteriology·F W Forney, A J Markovetz
Dec 1, 1979·Journal of Bacteriology·J A WilliamsA J Markovetz
Oct 1, 1972·Journal of Bacteriology·W T Blevins, J J Perry
Sep 24, 1969·Biochemical and Biophysical Research Communications·F W Forney, A J Markovetz
May 6, 2011·Chemical Reviews·Hannes LeischPeter C K Lau

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