Bacterial Small Regulatory RNAs and Hfq Protein

Biochemistry. Biokhimii︠a︡
V N Murina, A D Nikulin

Abstract

Small regulatory RNA (sRNA) is a unique noncoding RNA involved in regulation of gene expression in both eukaryotic and bacterial cells. This short review discusses examples of positive and negative translation regulation by sRNAs in bacteria and participation of Hfq in these processes. The importance of structure investigation of nucleotide-protein and RNA-protein complexes for designing a model of Hfq interaction with both mRNA and sRNA simultaneously is demonstrated.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Sep 1, 1983·Cell·R W Simons, N Kleckner
Oct 15, 1998·Proceedings of the National Academy of Sciences of the United States of America·R A LeaseM Belfort
Oct 15, 1998·Proceedings of the National Academy of Sciences of the United States of America·Nadim MajdalaniSusan Gottesman
Jan 5, 2002·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·A Ikekawa, S Ikekawa
Jan 24, 2002·Molecular Cell·Thorleif MøllerPoul Valentin-Hansen
Mar 28, 2002·Proceedings of the National Academy of Sciences of the United States of America·Eric Massé, Susan Gottesman
Jul 10, 2002·Proceedings of the National Academy of Sciences of the United States of America·Olga KandrorAlfred L Goldberg
Sep 17, 2003·Genes & Development·Eric MasséSusan Gottesman
Jan 24, 2004·The EMBO Journal·Thomas A Geissmann, Danièle Touati
Mar 11, 2004·Molecular Microbiology·Poul Valentin-HansenChristina Udesen
Apr 6, 2004·Current Opinion in Microbiology·Gisela StorzAixia Zhang
Oct 7, 2004·Journal of Bacteriology·Shuo ChenGisela Storz
Oct 19, 2004·Annual Review of Microbiology·Susan Gottesman
Feb 1, 2005·Developmental Biology·Ralf Dahm
Nov 30, 2005·Molecular Microbiology·Anders Aamann RasmussenPoul Valentin-Hansen
Mar 22, 2006·Proceedings of the National Academy of Sciences of the United States of America·Teppei MoritaHiroji Aiba
Mar 27, 2007·Current Opinion in Microbiology·Jonathan Livny, Matthew K Waldor
Mar 27, 2007·Current Opinion in Microbiology·Hiroji Aiba
Jun 8, 2007·Current Opinion in Microbiology·Shoshy Altuvia
Jul 31, 2007·Protein Science : a Publication of the Protein Society·Véronique ArluisonMaxim V Sukhodolets
Jul 29, 2008·RNA·Toby J Soper, Sarah A Woodson
Nov 6, 2009·Proceedings of the National Academy of Sciences of the United States of America·Todd M LinkRichard G Brennan
Nov 28, 2009·Nucleic Acids Research·Jesper Sejrup NielsenBirgitte Haahr Kallipolitis
Dec 10, 2009·Proceedings of the National Academy of Sciences of the United States of America·Dominik JägerRuth A Schmitz
Oct 29, 2010·Cold Spring Harbor Perspectives in Biology·Susan Gottesman, Gisela Storz
Jul 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Evelyn Sauer, Oliver Weichenrieder
Oct 8, 2011·Genes & Development·Weiwei WangYunyu Shi
Nov 22, 2011·Molecular Microbiology·S Marzi, P Romby
Mar 6, 2012·The EMBO Journal·Chase L BeiselGisela Storz
May 31, 2012·Proceedings of the National Academy of Sciences of the United States of America·Evelyn SauerOliver Weichenrieder
Jan 30, 2013·Biochemical Society Transactions·Daniela PrasseRuth A Schmitz
Jan 31, 2013·The Journal of Biological Chemistry·Nicholas De LaySusan Gottesman
Feb 9, 2013·RNA Biology·Carol J Wilusz, Jeffrey Wilusz
Apr 23, 2013·Nucleic Acids Research·Weiwei WangYunyu Shi
Jun 19, 2013·Nucleic Acids Research·Subrata PanjaSarah A Woodson

Citations

Apr 18, 2019·Annals of the New York Academy of Sciences·José Vicente Gomes-Filho, Lennart Randau
Oct 13, 2020·Frontiers in Cellular and Infection Microbiology·Guang YangLigui Wang

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