Bacterial Therapy and Mitochondrial Therapy

Biochemistry. Biokhimii︠a︡
V A PopkovD B Zorov

Abstract

Current methods for treatment of cellular and organ pathologies are extremely diverse and constantly evolving, going beyond the use of drugs, based on chemical interaction with biological targets to normalize the functions of the system. Because pharmacological approaches are often untenable, recent strategies in the therapy of different pathological conditions are of particular interest through introducing into the organism of some living system or its components, in particular, bacteria or isolated subcellular structures such as mitochondria. This review describes the most interesting and original examples of therapy using bacteria and mitochondria, which in perspective can dramatically change our views on the principles for the treatment of many diseases. Thus, we analyze such therapeutic effects from the perspective of the similarities between mitochondria and bacteria as the evolutionary ancestors of mitochondria.

References

Jan 11, 1992·Archives of Surgery·T LeVoyerB A Pruitt
Sep 29, 1989·Biochemical and Biophysical Research Communications·Y MizunoY Kagawa
Nov 1, 1985·The Journal of Clinical Investigation·E Braunwald, R A Kloner
Feb 18, 1982·Nature·M A Clark, J W Shay
Jan 9, 1999·Medical Hypotheses·E R Bolte
Aug 13, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sydney M FinegoldAjay Kaul
Feb 14, 2004·Science·Amin RustomHans-Hermann Gerdes
Jun 29, 2004·Journal of Clinical Gastroenterology·Thomas J BorodySteven Siarakas
Feb 4, 2006·The Journal of Trauma·Kentaro ShimizuHisashi Sugimoto
Dec 20, 2007·Journal of Cellular and Molecular Medicine·E Y PlotnikovD B Zorov
Jan 1, 2008·Acta Neurochirurgica. Supplement·Gunes A AygokRoss M Bullock
Jun 17, 2009·Biochemical and Biophysical Research Communications·Marta OnopiukKrzysztof Zabłocki
May 9, 2012·Nature Medicine·Darwin J Prockop
Jul 4, 2012·Nucleic Acids Research·Yi-Wei Yang, Michael D Koob
May 18, 2013·Cell Death & Disease·O KryskoD V Krysko
Oct 23, 2013·Biological Psychiatry·Philip W J Burnet, Philip J Cowen
Dec 19, 2014·Biochemistry. Biokhimii︠a︡·D B ZorovP S Savina
Jan 13, 2015·Cell Death and Differentiation·X Wang, H-H Gerdes
Mar 17, 2015·Current Psychiatry Reports·Emily G SeveranceRobert H Yolken
Mar 24, 2015·Bioscience Reports·Imran UllahGyu Jin Rho
Sep 16, 2015·Current Opinion in Clinical Nutrition and Metabolic Care·Timothy G Dinan, John F Cryan
Feb 4, 2016·Circulation Research·Conrad P HodgkinsonVictor J Dzau
May 1, 2016·Clinical and Translational Medicine·James D McCullyDouglas B Cowan
Jun 9, 2016·BioResearch Open Access·Walter H MoosKosta Steliou
Jun 19, 2016·Current Research in Translational Medicine·P Menasché, V Vanneaux

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Citations

Jul 28, 2020·Ageing Research Reviews·Santhanam ShanmughapriyaKalimuthusamy Natarajaseenivasan
May 4, 2021·Critical Reviews in Microbiology·Francis M CavalloJan Maarten van Dijl

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