Feb 9, 2011

Bacterial transport of sulfate, molybdate, and related oxyanions

Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
Esther Aguilar-BarajasCarlos Cervantes

Abstract

Sulfur is an essential element for microorganisms and it can be obtained from varied compounds, sulfate being the preferred source. The first step for sulfate assimilation, sulfate uptake, has been studied in several bacterial species. This article reviews the properties of different bacterial (and archaeal) transporters for sulfate, molybdate, and related oxyanions. Sulfate uptake is carried out by sulfate permeases that belong to the SulT (CysPTWA), SulP, CysP/(PiT), and CysZ families. The oxyanions molybdate, tungstate, selenate and chromate are structurally related to sulfate. Molybdate is transported mainly by the high-affinity ModABC system and tungstate by the TupABC and WtpABC systems. CysPTWA, ModABC, TupABC, and WtpABC are homologous ATP-binding cassette (ABC)-type transporters with similar organization and properties. Uptake of selenate and chromate oxyanions occurs mainly through sulfate permeases.

Mentioned in this Paper

Microorganism
Selenium Compounds, Inorganic
Sulfates, Inorganic
Sulp
Sulfate Assimilation
Cyclosporine
Uptake
Sulfur
Selenic Acid, Disodium Salt, Decahydrate
Tungsten Compounds

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