Bacterial vaginosis: prevalence and predictive value for premature delivery and neonatal infection in women with preterm labour and intact membranes

European Journal of Obstetrics, Gynecology, and Reproductive Biology
F GoffinetG Paul

Abstract

Assess the predictive values of bacterial vaginosis (BV) for preterm delivery (PD) and neonatal infection and compare them with standard markers of infection among women with preterm labour (PL). Prospective blinded study in a tertiary referral centre in Paris. Women hospitalised for PL with intact membranes at a term between 24 and 34 weeks were included. Vaginal fluid, collected at inclusion was Gram-stained, scored, and interpreted according to Nugent's criteria. Out of 354 women tested, 254 had normal flora (72.3%), 76 intermediate (21.7%) and 24 BV (6.8%). A history of spontaneous miscarriage after 14 weeks was the only risk factor significantly associated with BV. BV was not significantly associated with PD<35 weeks or neonatal infection. Very preterm delivery (before 33 weeks) was significantly associated with the flora grade (P=0.02): women with normal, intermediate and abnormal flora, respectively had 27 (10.6%), 14 (18.4%) and 6 (25.0%) births before 33 weeks. Of the markers tested, the highest risk of very preterm delivery was associated with BV (odds ratio 2.95, 95% CI (1.1-0.8.1)) and CRP>20mg/dl (4.23 95% CI (1.8-9.7)). Predictive value of BV for preterm birth before 33 weeks were: sensitivity 12.8%, specificity 9...Continue Reading

References

May 1, 1992·American Journal of Obstetrics and Gynecology·R S GibbsR L Sweet
Aug 1, 1988·American Journal of Obstetrics and Gynecology·R BejarR Resnik
Jul 1, 1997·Acta Obstetricia Et Gynecologica Scandinavica·A R GoffengB Andersch
Jan 23, 1999·Obstetrics and Gynecology·L M PastoreU S Kreaden
May 18, 2000·The New England Journal of Medicine·R L GoldenbergW W Andrews
Jun 10, 2000·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D V SurbekW Holzgreve
Dec 16, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·M Kurkinen-RätyP Jouppila
May 23, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·M MorrisM Catchpole

❮ Previous
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Citations

Dec 8, 2009·Archives of Gynecology and Obstetrics·Laura DonatiGiancarlo Paradisi
Jan 24, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Harald Leitich, Herbert Kiss
Jun 3, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jean-Pierre MenardDidier Raoult
Feb 2, 2010·Sexually Transmitted Diseases·Jenifer E Allsworth
Apr 25, 2013·Current Opinion in Infectious Diseases·Marianne CunningtonPaul Heath
Apr 4, 2015·Critical Reviews in Microbiology·Mathys Jacobus RedelinghuysMarleen Magdalena Kock
Mar 2, 2012·Journal de gynécologie, obstétrique et biologie de la reproduction·E Bothuyne-QuesteD Subtil
Dec 24, 2011·Gynécologie, obstétrique & fertilité·J-P Menard, F Bretelle
Dec 24, 2011·Journal de gynécologie, obstétrique et biologie de la reproduction·E PetitD Subtil
Nov 9, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Pierre-Yves Ancel
Aug 23, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mirjana BogavacBiljana Bozin
Sep 10, 2005·American Journal of Obstetrics and Gynecology·Leonardo PereiraPaul Nyirjesy
Sep 23, 2014·Best Practice & Research. Clinical Obstetrics & Gynaecology·Ido Solt
Oct 21, 2016·Journal of Cytology·Gözde IşikMehmet Sinan Beksaç
Oct 8, 2016·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Tatiana RumyantsevaMagnus Unemo
Oct 30, 2016·Journal de gynécologie, obstétrique et biologie de la reproduction·G KayemM Doret
Oct 30, 2016·Journal de gynécologie, obstétrique et biologie de la reproduction·G Brabant
Feb 18, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Lisa M StarrDaniel Dufort
Dec 23, 2009·Obstetrics and Gynecology·Jean Pierre MenardFlorence Bretelle
Jan 27, 2019·Scientific Reports·Masao ShimaokaNoriomi Matsumura
Dec 13, 2006·Central European Journal of Public Health·Sayeste DemirezenM Sinan Beksaç

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