Bactericidal activity of combinations of penicillin or clindamycin with gentamicin or streptomycin against species of viridans streptococci.

Antimicrobial Agents and Chemotherapy
R DupervalJ A Washington

Abstract

Checkerboard bactericidal studies were performed with two strains each of Streptococcus mitis, S. salivarius, and S. sanguis, and the results were analyzed by the use of isobolograms. Synergy between penicillin and streptomycin or gentamicin was demonstrated with four strains, representing two of S. salivarius, one of S. sanguis, and one of S. mitis; the remainder were either too susceptible or too resistant to be analyzed. Clindamycin with streptomycin or gentamicin acted synergistically with three strains, representing two of S. sanguis and one of S. salivarius; the remainder were either too susceptible or too resistant to be analyzed.

Citations

Oct 1, 1991·Oral Microbiology and Immunology·L Kimmel, N Tinanoff
Feb 1, 1977·Chest·F R Sattler, J Ruskin
Feb 24, 2015·International Journal of Antimicrobial Agents·Torgny SunnerhagenMagnus Rasmussen
Jun 7, 2011·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·S MuttaiyahS A Roberts
Apr 21, 1988·The New England Journal of Medicine·J M Greally

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