Bactericidal mode of action of plantaricin C.

Applied and Environmental Microbiology
B GonzalezW N Konings

Abstract

Plantaricin C is a bacteriocin produced by Lactobacillus plantarum LL441 that kills sensitive cells by acting on the cytoplasmic membrane. In contrast to its lack of impact on immune cells, plantaricin C dissipates the proton motive force and inhibits amino acid transport in sensitive cells. In proteoliposomes, plantaricin C dissipates the transmembrane electrical potential, and in liposomes, it elicits efflux of entrapped carboxy-fluorescein. It is concluded that plantaricin C is a pore-forming bacteriocin that functions in a voltage-independent manner and does not require a specific protein receptor in the target membrane.

Associated Datasets

References

Sep 1, 1990·The Journal of Applied Bacteriology·A GálvezM Maqueda
Jan 1, 1989·Critical Reviews in Microbiology·W N KoningsA J Driessen
Jan 1, 1993·Methods in Enzymology·A J Driessen, W N Konings
Mar 1, 1993·European Journal of Biochemistry·M J GarceráW N Konings

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Citations

May 12, 2001·FEMS Microbiology Reviews·O McAuliffeC Hill
Dec 26, 2006·Journal of Food Protection·Stéphane Caillet, Monique Lacroix
Aug 31, 2010·Applied and Environmental Microbiology·Eduardo SánchezNorma Heredia
Oct 23, 2010·Journal of Basic Microbiology·Han-Sheng GongHui Wang
Sep 1, 2013·Probiotics and Antimicrobial Proteins·Deeplina Das, Arun Goyal
Apr 3, 2001·Applied and Environmental Microbiology·C HerranzM L Chikindas
Apr 10, 1999·Letters in Applied Microbiology·T J MontvilleY Chen
Apr 28, 2000·Microbiology·B MartínezJ E Suárez
Sep 22, 1999·European Journal of Biochemistry·D L TurnerJ E Suárez
Oct 20, 2011·The Journal of Antibiotics·Aman Preet SinghPraveen Rishi
Sep 7, 2012·Proceedings. Biological Sciences·J J Leisner, J Haaber
Oct 22, 2014·Antimicrobial Agents and Chemotherapy·Rebeca MartínJuan E Suarez
Dec 1, 2012·Probiotics and Antimicrobial Proteins·Clara RocesBeatriz Martínez
Aug 5, 2000·Applied and Environmental Microbiology·M C Martínez-CuestaG Buist
Apr 7, 2006·Applied and Environmental Microbiology·Imke WiedemannBeatriz Martínez
Feb 17, 1998·Applied and Environmental Microbiology·O McAuliffeT Abee
Sep 8, 2017·Critical Reviews in Food Science and Nutrition·Eldin Maliyakkal JohnsonJoo Won Suh
Oct 12, 2017·Natural Product Reports·Walaa K MousaNathan A Magarvey
Dec 29, 2020·Critical Reviews in Food Science and Nutrition·Silpa S, Rupachandra S
Sep 3, 1998·Applied and Environmental Microbiology·J M BárcenaJ E Suárez

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