Bacteriocin from Bacillus megaterium ATCC 19213: comparative studies with megacin A-216.

Journal of Bacteriology
M A Von Tersch, B C Carlton

Abstract

A bacteriocin produced by Bacillus megaterium ATCC 19213 was identified, purified, and compared with megacin A from B. megaterium 216. The ATCC 19213 bacteriocin was inducible with mitomycin C and showed phospholipase A activity. Both megacin A-216 and megacin A-19213 contained two dissimilar polypeptide subunits. Megacin A-216 contains a 30,000-dalton alpha subunit and a 15,000-dalton beta subunit. Megacin A-19213 is composed of an alpha subunit 18,000 daltons in mass and a beta subunit about 7,500 daltons in mass. No sequence similarities between alpha and beta subunits of either megacin were detected. The two megacins were further distinguished by quantitative differences in activity spectra and by immunodiffusion analyses.

References

Nov 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·K Schaller, M Nomura
Sep 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·K S Jakes, N D Zinder
Nov 1, 1981·Journal of Bacteriology·K K FrickJ Konisky
Aug 1, 1983·Journal of Bacteriology·M A Von Tersch, B C Carlton
Sep 4, 1954·Nature·G IVANOVICS, L ALFOLDI
Oct 1, 1958·Journal of General Microbiology·G IVANOVICS, E NAGY
May 1, 1964·Journal of General Microbiology·I B HOLLAND, C F ROBERTS
Dec 28, 1964·Annals of the New York Academy of Sciences·B J DAVIS
Jun 1, 1965·Journal of Molecular Biology·I B HOLLAND
Aug 1, 1959·Journal of General Microbiology·G IVANOVICSE NAGY

❮ Previous
Next ❯

Citations

Aug 11, 2010·FEMS Microbiology Reviews·Hikmate AbriouelAntonio Gálvez
Jun 13, 2003·Folia Microbiologica·S CetinkayaC Cökmüş
May 7, 2003·Applied and Environmental Microbiology·Trine NilsenHelge Holo
Jan 4, 2019·Applied Microbiology and Biotechnology·Snizhana OlishevskaEric Déziel
Jun 27, 2020·Biochimica Et Biophysica Acta. Reviews on Cancer·Atieh YaghoubiWilliam C Cho
Jun 1, 1995·Microbiological Reviews·R W JackB Ray
Aug 1, 1983·Journal of Bacteriology·M A Von Tersch, B C Carlton

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.