Bacteriological profile and antibiotic susceptibility of neonatal sepsis in neonatal intensive care unit of a tertiary hospital in Nepal

BMC Pediatrics
Bhishma PokhrelPinky Baral

Abstract

Neonatal sepsis, one of the leading causes of mortality in neonatal intensive care units (NICU) of developing countries like Nepal, is often not extensively studied. In order to decrease the morbidity and mortality associated with neonatal sepsis, neonatologists should have a keen knowledge of the existing bacteriological flora and their antibiotic susceptibility pattern. In this study, we aim to determine the bacteriological profile and antibiotic susceptibility pattern of culture positive neonatal sepsis in the NICU of a tertiary teaching hospital in Nepal. This was a retrospective cross-sectional study of all blood culture positive sepsis cases among neonates admitted to the neonatal intensive care unit of Patan Hospital, Nepal between April 15, 2014 and April 15, 2017. All neonates with a clinical suspicion of sepsis with a positive blood culture were identified. Patient demographics, clinical details, maternal risk factors, and laboratory data including bacteriological profiles and antimicrobial susceptibilities were recorded and analyzed. Of the 336 neonates admitted in the NICU, 69 (20.5%) had culture-positive sepsis. The majority were early-onset sepsis (n = 54, 78.3%) and were among the preterm babies (n = 47, 68.1%). ...Continue Reading

References

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Citations

Feb 28, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Jing WangTing Zhang
May 19, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Julia JohnsonYukari C Manabe
Mar 1, 2021·BMC Infectious Diseases·Dharshni PillayYesholata Mahabeer
Apr 4, 2021·Infectious Disease Reports·Arlenis OlivaDianelys Quiñones
May 1, 2021·Tropical Medicine and Infectious Disease·Bijendra Raj RaghubanshiBal Man Singh Karki
May 12, 2021·Antimicrobial Agents and Chemotherapy·Christopher A DarlowWilliam Hope
Jul 2, 2021·BioMed Research International·Desalegne Amare ZelellwSolomon Emishaw
Jul 22, 2021·Infection and Drug Resistance·Yue QiuMei Zeng
Nov 23, 2021·Frontiers in Immunology·Erick Sánchez-SalgueroLeopoldo Santos-Argumedo

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Methods Mentioned

BETA
cesarean section

Software Mentioned

Statistical Package for Social Sciences ( SPSS )
Taz
Pip
[UNK] for Mobile

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