Bacteriology and Antibiotic Susceptibility Patterns among Neonates Diagnosed of Omphalitis at a Tertiary Special Care Baby Unit in Western Uganda

International Journal of Pediatrics
Munanura TuryasiimaYamile Enedina Arias Ortiz

Abstract

Newborn infections remain a major cause of morbidity and mortality among neonates in low-income countries. Clinical diagnosis for omphalitis in such settings is possible but this does not depict the microbiological characteristics of the involved organisms, and clinicians have often prescribed empirical antibiotics in neonates with omphalitis, despite an increasing burden of antibiotic resistance. A hospital-based cross-sectional study was conducted to evaluate the bacteriology and antibiotic susceptibility patterns among neonates diagnosed with omphalitis at the special care baby unit (SCBU) of Kampala International University-Teaching Hospital (KIU-TH), western Uganda from March to June 2019. Sixty-five (65) neonates with a clinical diagnosis of omphalitis were consecutively recruited in the study. Cord swabs were taken under sterile (aseptic) precautions from all neonates, and antibiotic susceptibility tests performed using the Kirby Bauer disk diffusion technique with commercially available antibiotics disks of ampicillin, cloxacillin, gentamicin, amikacin, cefotaxime, ceftriaxone, vancomycin, and imipenem on Mueller Hinton agar plates. The data was analyzed using STATA version 13.0, frequencies and proportions used to desc...Continue Reading

References

Jan 1, 1991·Scandinavian Journal of Infectious Diseases·H GüvençS Bektaş
Jan 27, 2004·The Pediatric Infectious Disease Journal·Kiran P Sawardekar
Oct 27, 2006·American Journal of Epidemiology·Luke C MullanyJames M Tielsch
Dec 16, 2011·Journal of Infection in Developing Countries·Fatima MirAnita K M Zaidi
Aug 31, 2016·Pediatrics·Dan StewartUNKNOWN COMMITTEE ON FETUS AND NEWBORN
Feb 22, 2017·BMC Pregnancy and Childbirth·Patricia S Coffey, Siobhan C Brown

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