Bacteriophage imaging: past, present and future

Research in Microbiology
Gabriel Mf AlmeidaLotta-Riina Sundberg

Abstract

The visualization of viral particles only became possible after the advent of the electron microscope. The first bacteriophage images were published in 1940 and were soon followed by many other publications that helped to elucidate the structure of the particles and their interaction with the bacterial hosts. As sample preparation improved and new technologies were developed, phage imaging became important approach to morphologically classify these viruses and helped to understand its importance in the biosphere. In this review we discuss the main milestones in phage imaging, how it affected our knowledge on these viruses and recent developments in the field.

Citations

Aug 25, 2020·Centaurus; International Magazine of the History of Science and Medicine·Flavio D'Abramo, Sybille Neumeyer
Jan 26, 2021·Beilstein Journal of Nanotechnology·Matthias SchmidtIlari J Maasilta
Mar 5, 2021·Bioconjugate Chemistry·Caitlin M CarmodySam R Nugen

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