PMID: 6402605Apr 1, 1983Paper

Bacteriophage SPO1 structure and morphogenesis. I. Tail structure and length regulation

Journal of Virology
M L Parker, F A Eiserling

Abstract

Bacteriophage SPO1, a structually complex phage with hydroxymethyl uracil replacing thymine, has been studied by structural and chemical methods with the aim of defining the virion organization. The contractile tail of SPO1 consists of a complex baseplate, a tail tube, and a 140-nm-long sheath composed of stacked disks (4.1 nm repeat), each containing six subunits of molecular weight 60,300. The subunits are arranged in six parallel helices, each with a helical screw angle (omega 0) of 22.5 degrees. The baseplate was shown to undergo a structural rearrangement during tail contraction into a hexameric pinwheel. A mutation in gene 8 which produced unattached heads and tails also produced tails of different lengths. The tail length distribution suggests that the smallest integral length increment is a single disk of subunits. The structural arrangement of subunits in long tails is identical to that of normal tails, and the tails can contract. Many of the long tails showed partial stain penetration within the tail tube to a point which coincides with the top of a unit-length tail. The implications of these findings with respect to tail length regulation are discussed.

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Citations

Aug 18, 2010·Archives of Virology·Jochen KlumppHans-Wolfgang Ackermann
Feb 21, 2009·The EMBO Journal·Anastasia A AksyukMichael G Rossmann
Aug 27, 2010·The Journal of General Virology·Yuri G KuznetsovAlexander McPherson
Feb 9, 2011·Letters in Applied Microbiology·W-J LeeJ A Heinemann
Sep 8, 2010·Journal of Industrial Microbiology & Biotechnology·Eun Ju KimYoung Nam Lee
Jan 16, 2019·Viruses·Eugenijus ŠimoliūnasRolandas Meškys
Jan 1, 1995·Micron : the International Research and Review Journal for Microscopy·E Kellenberger, H Wunderli-Allenspach
Apr 1, 1983·Journal of Virology·M L ParkerF A Eiserling
Apr 1, 1983·Journal of Virology·M L Parker, F A Eiserling
Oct 19, 2004·Journal of Bacteriology·Sandra Chibani-ChennoufiHarald Brüssow
Oct 28, 2009·BMC Microbiology·Rob LavigneAndrew M Kropinski
Mar 17, 2009·Journal of Molecular Biology·Charles R StewartMarisa L Pedulla

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