Bacteriophages and transplantation tolerance

Transplantation Proceedings
Andrzej GórskiM Nowaczyk

Abstract

Our recent findings suggest that bacteriophages (phages) may not only eliminate bacteria, but also modulate immune functions. In this communication, we demonstrate that phages may strongly inhibit human T-cell activation and proliferation as well as activation of the nuclear transcription factor NF-kappaB in response to a viral pathogen. Phage administration in vivo can diminish cellular infiltration of allogeneic skin allografts. Thus, phage treatment should be considered in antibiotic-resistant posttransplantation infections. Furthermore, phages could find a broader application in clinical transplantation.

References

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Citations

Feb 1, 2006·Medical Microbiology and Immunology·Anna PrzerwaAndrzej Górski
Feb 3, 2009·Clinical and Experimental Medicine·Aneta KurzepaAndrzej Górski
Apr 8, 2009·Clinical and Experimental Medicine·Ryszard MiedzybrodzkiAndrzej Górski
Sep 26, 2009·Clinical and Experimental Medicine·Krystyna DabrowskaAndrzej Górski
Jun 20, 2013·Nature Immunology·Breck A Duerkop, Lora V Hooper
Oct 1, 2005·Archives of Virology·K DabrowskaA Górski
Sep 13, 2011·Expert Review of Anti-infective Therapy·Ben BurrowesMark C Enright
Aug 27, 2011·Current Opinion in Microbiology·Timothy K Lu, Michael S Koeris
Mar 11, 2008·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Keith E FollmarJeffrey R Marcus
Nov 15, 2013·Bacteriophage·Alexandra Henein
Apr 11, 2008·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Jan Borysowski, Andrzej Górski
Mar 24, 2006·FEMS Immunology and Medical Microbiology·Andrzej GórskiRyszard Miedzybrodzki
Aug 12, 2010·FEMS Immunology and Medical Microbiology·Sławomir LetkiewiczAndrzej Górski
May 5, 2016·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Justin D Glenn, Ellen M Mowry
Aug 27, 2013·PloS One·Paulina MiernikiewiczAndrzej Górski
Jun 11, 2016·Annals of the New York Academy of Sciences·Felix BroeckerKarin Moelling
Jul 30, 2016·Frontiers in Microbiology·Paulina MiernikiewiczKrystyna Dąbrowska
Sep 9, 2016·Annual Review of Microbiology·Nicolás RascovanChristelle Desnues
Apr 25, 2017·Future Microbiology·Andrzej GórskiJan Borysowski
Jan 24, 2018·Experimental Biology and Medicine·Andrzej GórskiJan Borysowski
Sep 1, 2017·Immunological Reviews·Jeremy J Barr
Dec 22, 2017·British Journal of Pharmacology·Amanda Forde, Colin Hill
Dec 22, 2017·Clinical and Experimental Immunology·A GórskiJ Borysowski
Dec 5, 2017·BioMed Research International·Ryszard MiędzybrodzkiAndrzej Górski
May 15, 2018·Frontiers in Immunology·Andrzej GórskiJan Borysowski
Jan 29, 2019·Frontiers in Microbiology·Andrzej GórskiBeata Weber-Dąbrowska
Jul 13, 2018·Frontiers in Microbiology·Anushila Chatterjee, Breck A Duerkop
May 11, 2019·Nature Reviews. Urology·Andrea GarrettoCatherine Putonti
May 31, 2019·Reviews in Medical Virology·Rizka O A Jariah, Mohamad S Hakim
Oct 5, 2019·Mediators of Inflammation·Anshul Sinha, Corinne F Maurice
Sep 24, 2020·International Journal of Microbiology·Vijaya Nath MishraRameshwar Nath Chaurasia
Dec 15, 2020·Current Opinion in Biotechnology·Christiaan R de VriesPaul L Bollyky
Feb 5, 2021·Frontiers in Microbiology·Abrar Senhaji-KachaMeritxell Garcia-Quintanilla
Feb 9, 2021·Frontiers in Veterinary Science·Souvik Ghosh, Yashpal S Malik
Mar 5, 2021·Vavilovskiĭ Zhurnal Genetiki I Selekt︠s︡ii·A Yu KashnikovN A Novikova
Mar 25, 2021·The Journal of Experimental Medicine·Yuhao LiMegan T Baldridge
Nov 28, 2020·Trends in Microbiology·Katie BodnerMarkus W Covert

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