PMID: 2116453Jun 1, 1990Paper

Bacteriostatic and bactericidal actions of boric acid against bacteria and fungi commonly found in urine

Journal of Clinical Pathology
P D Meers, C K Chow

Abstract

Boric acid has been used for over 20 years to preserve urine while in transit for bacteriological examination. It has been suggested that it may be toxic for some urinary pathogens. To investigate this several strains of bacteria and fungi commonly found in urine were exposed to different concentrations of boric acid in nutrient broth. Viable counts were made at the outset and at intervals for up to 24 hours at room temperature to detect bacteriostatic or bactericidal effects. At concentrations between 10 and 20 g/l boric acid was bacteriostatic or fungistatic for very nearly all the common urinary pathogens. At 10 g/l boric acid was weakly bactericidal for some strains of Acinetobacter calcoaceticus and Pseudomonas aeruginosa, though higher concentrations were bacteriostatic only. Group B streptococci varied in their response to boric acid, but for most of them 10 or 20 g/l was satisfactorily bacteriostatic. It is concluded that boric acid is rarely toxic, and when it is, the effect is usually sufficiently delayed to be of only theoretical importance.

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Citations

Dec 9, 2008·The Journal of Antimicrobial Chemotherapy·Francesco De SetaBryan Larsen
Oct 25, 2013·Indian Journal of Pathology & Microbiology·Suma B AppannanavarNeelam Taneja
Jul 9, 1999·Journal of Clinical Pathology·T GillespieR G Masterton
Feb 13, 2016·Biological Trace Element Research·Zafer SayinAsli Sakmanoglu
Feb 24, 2009·Analytical Biochemistry·M TsivouC G Georgakopoulos
Oct 5, 2011·The Journal of Small Animal Practice·M RowlandsR Burrow
Aug 21, 2012·Microbiology·Martin SchmidtMichael P Boyer
Jun 1, 2015·International Journal of Pediatric Otorhinolaryngology·Marie-Astrid LefebvreSam J Daniel
Jul 16, 2016·Dental Materials : Official Publication of the Academy of Dental Materials·Saeki MikiSatoshi Imazato
Sep 23, 2016·Clinical Journal of the American Society of Nephrology : CJASN·Callen Giesen, John C Lieske
Feb 1, 2018·Korean journal of family medicine·Indri AdriztinaYuliani Mardiati Lubis
Sep 30, 2017·Journal of the American Veterinary Medical Association·Anna UhlKatrina R Viviano
Jan 9, 2020·Maternal & Child Nutrition·Husein MohammedAregash Samuel
Oct 7, 2020·American Journal of Human Biology : the Official Journal of the Human Biology Council·Virginia J Vitzthum
Jul 1, 1997·Annals of Clinical Biochemistry·G R Jones
Jul 3, 2021·Nutrition and Metabolic Insights·Husein MohammedAregash Samuel

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