Balancing cell behavior at boundaries

The Journal of Cell Biology
D G Wilkinson

Abstract

The restriction of cell intermingling across boundaries is essential for the establishment of discrete tissues. Eph receptor signaling prevents intermingling at many boundaries. In this issue, Luu et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201409026) report a parallel pathway, mediated by Wnt signaling, Snail1, and paraxial protocadherin (PAPC). This pathway establishes a distinctive organization of cell adhesion and intercellular gaps at the interface between tissues.

References

Feb 8, 2003·The EMBO Journal·Masamitsu TanakaHaruhiko Sugimura
Apr 6, 2005·Developmental Cell·Dörthe JülichUNKNOWN Tübingen 2000 Screen Consortium
Dec 18, 2010·Nature Reviews. Genetics·Christian DahmannMichael Brand
Jan 5, 2012·Cold Spring Harbor Perspectives in Biology·Eduard Batlle, David G Wilkinson
Aug 21, 2014·Development·François Fagotto
Dec 3, 2014·Developmental Biology·Jordi CayusoDavid G Wilkinson
Dec 9, 2014·Cell Adhesion & Migration·Francois FagottoNazanin Rohani
Mar 18, 2015·The Journal of Cell Biology·Olivia LuuRudolf Winklbauer

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Citations

Jul 5, 2016·Genome Génome / Conseil National De Recherches Canada·Siti W Mohd-ZinNoraishah M Abdul-Aziz
Oct 8, 2019·Molecular Biology and Evolution·Aida ArcasM Ángela Nieto

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