Balloon aortic valvuloplasty to bridge and triage patients in the era of trans-catheter aortic valve implantation

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Christopher J MalkinAjay Sinhal

Abstract

To describe the use of balloon aortic valvuloplasty (BAV) as a method of selecting patients for definitive aortic valve therapy. BAV is a temporising treatment for aortic stenosis, previously used for palliation or bridge to surgery. The advent of transcatheter aortic valve implantation (TAVI) has developed a new indication for BAV-as a therapeutic trial. This is a descriptive series of 33 consecutive patients treated between 2008 and 2010. Standard BAV retrograde technique was used. Hemodynamic results and survival were recorded; destination valve therapy was offered based on clinical response. The reasons for nonresponse were explored. Procedural success was achieved in all patients, valve area improved 0.36 ± 0.14 cm(2) , mean gradient by 20 ± 9.5 mm Hg and peak catheter gradient by 28.2 ± 17 mm Hg. Thirty-day mortality was 3% and 6-month mortality 15%. Twelve patients had no clinical improvement and were managed conservatively; two others demonstrated temporary occlusion of the left main by native leaflets during BAV. The remaining 19 patients improved and were offered valve therapy (10 TAVI and five aortic valve replacement). Post hoc analysis of the groups found higher prevalence of left ventricular impairment (90% vs. 29...Continue Reading

References

Mar 29, 2007·Circulation·Hidehiko HaraRobert S Schwartz
Oct 23, 2009·The Journal of Thoracic and Cardiovascular Surgery·Tristan D YanPaul G Bannon
Feb 11, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Ronak RajaniDavid Hildick-Smith
Feb 11, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Eric YamenWilliam F Fearon
Jun 15, 2010·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Eugenio StabilePaolo Rubino
Jul 14, 2010·Journal of Interventional Cardiology·Samir R KapadiaE Murat Tuzcu
Oct 22, 2010·The New England Journal of Medicine·Martin B LeonUNKNOWN PARTNER Trial Investigators
Nov 16, 2010·European Heart Journal·Thierry LefèvreUNKNOWN PARTNER EU Investigator Group
Feb 16, 2011·Circulation·Nikolaus JanderChrista Gohlke-Bärwolf
May 10, 2011·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Claire-Marie TissotAlec Vahanian
Jun 7, 2011·The New England Journal of Medicine·Craig R SmithUNKNOWN PARTNER Trial Investigators

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Citations

Sep 7, 2012·Clinical Medicine Insights. Cardiology·Patrick P Hu
Dec 10, 2014·Interactive Cardiovascular and Thoracic Surgery·Nnamdi NwaejikeMark Field
Aug 16, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Marzena DaniecDariusz Dudek
Jun 2, 2017·Heart·Dario BongiovanniChristian Kupatt
Feb 21, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Amar Krishnaswamy, E Murat Tuzcu
May 13, 2017·Circulation. Cardiovascular Interventions·Mohamad AlkhouliCharanjit S Rihal
Jan 21, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Deborah TabachnickDavid L Brown
Feb 18, 2020·JACC. Cardiovascular Interventions·Akram KawsaraMohamad Alkhouli

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