Balo's concentric sclerosis: an update and comprehensive literature review.

Reviews in the Neurosciences
Ali Amini HarandiMohammad Ali Sahraian

Abstract

Balo's concentric sclerosis (BCS) is considered a variant of multiple sclerosis characterized by concentric lamella of alternating demyelinated and partially myelinated tissues. It is a rare and a relatively acute condition. Attacks may proceed rapidly over weeks or months, typically without remission, like Marburg's variant, resulting in death or severe disability. However, the majority of cases have a more benign, self-limiting course with spontaneous remission. Magnetic resonance imaging is a primary imaging modality in the diagnosis of BCS. Treatment with intense immunosuppression may be indicated in patients with more aggressive form. New reports reveal more evidence regarding the pathophysiology and treatment strategies.

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Citations

Jan 15, 2020·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·M E ShcheparevaA A Shabalina
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Jul 15, 2021·Journal of the Neurological Sciences·Jim Shenchu XieEdward Margolin
Aug 18, 2021·Annals of Medicine and Surgery·Hector R MartinezDavid Eugenio Hinojosa-Gonzalez

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