Barium sulphate preparations for use in double contrast examination of the upper gastrointestinal tract

The British Journal of Radiology
W AndersonD P Montgomery


Physical properties relevant to upper gastrointestinal radiology have been compared for five barium sulphate preparations and related to radiographic results. Evaluation of particles (size and stability) and whole suspension (dispersibility and fluidity) resulted in ranking of the preparations generally in accord with that based on radiological experience in double contrast examinations of the stomach. Experiments with extirpated pig stomach revealed a tendency for large particles in a low viscosity barium sulphate suspension to settle in mucosal grooves. This is believed to contribute to good radiographic definition of both the areae gastricae and small lesions. Particle size is therefore important and susceptibility to flocculation, a possible cause of random change in size during use, was assessed by measuring particle electrophoretic mobility under varying conditions; quantitative differences in suspension flow and dispersibility were also demonstrated. Fluidity and dispersibility together with rapid sedimentation of suitably sized particles resistant to flocculation underlie the successful use of low viscosity high density barium sulphate suspensions.


Jan 1, 1978·The Journal of Pharmacy and Pharmacology·L SaundersT Natunen
May 1, 1978·Clinical Radiology·D J LintottM J Noakes
Aug 1, 1977·The British Journal of Radiology·G M RobertsK T Evans
Jan 1, 1976·Clinical Radiology·J H Hunt, J F Anderson
Jul 1, 1973·Clinical Radiology·M A ZiervogelO P Fitzgerald-Finch
Jun 1, 1973·Australasian Radiology·J Kalokerinos
Jan 1, 1962·The Journal of Pharmacy and Pharmacology·W Anderson


Jan 1, 1986·Gastrointestinal Radiology·E SalomonowitzS Meryn
Jul 20, 2007·Abdominal Imaging·David A Boyajian, Alexander R Margulis
Dec 21, 2006·Academic Radiology·Stacy D O'Connor, Ronald M Summers

Related Concepts

Barium Sulfate (2: 1)
Radiographic contrast media
Gastric Juice
Particle Size

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