PMID: 8941544Nov 1, 1996Paper

Baroreceptor control of the cutaneous active vasodilator system

Journal of Applied Physiology
C G CrandallD L Kellogg

Abstract

We sought to identify whether reductions in cutaneous active vasodilation during simulated orthostasis could be assigned solely to cardiopulmonary or to carotid baroreflexes by unloading cardiopulmonary baroreceptors with low levels of lower body negative pressure (LBNP) or unloading carotid baroreceptors with external pressure applied over the carotid sinus area [carotid pressure (CP)]. Skin blood flow was measured at a site at which adrenergic function was blocked via bretylium tosylate iontophoresis and at an unblocked site. During LBNP of -5 and -10 mmHg in hyperthermia, neither heart rate (HR) nor cutaneous vascular conductance (CVC) at either site changed (P > 0.05 for both), whereas forearm vascular conductance (FVC) was reduced (-5 mmHg: from 21.6 +/- 4.8 to 19.8 +/- 4.1 FVC units, P = 0.05; -10 mmHg: from 22.3 +/- 4.0 to 19.3 +/- 3.7 FVC units, P = 0.002). LBNP of -30 mmHg in hyperthermia reduced CVC at both sites (untreated: from 51.9 +/- 5.7 to 43.2 +/- 5.1% maximum, P = 0.02; bretylium tosylate: from 60.9 +/- 5.4 to 53.2 +/- 4.4% maximum, P = 0.02), reduced FVC (from 23.2 +/- 3.6 to 18.1 +/- 3.3 FVC units; P = 0.002), and increased HR (from 83 +/- 4 to 101 +/- 3 beats/min; P = 0.003). Pulsatile CP (45 mmHg) did not ...Continue Reading

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Citations

May 8, 2000·Journal of Applied Physiology·J K PetersG W Mack
Mar 15, 2001·Journal of Applied Physiology·G W MackJ Peters
Dec 18, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jian CuiCraig G Crandall
Feb 4, 2003·Exercise and Sport Sciences Reviews·Manabu ShibasakiCraig G Crandall
Mar 1, 2003·Acta Physiologica Scandinavica·Craig G CrandallThad E Wilson
Feb 10, 2004·Journal of Applied Physiology·W Shane JourneayGlen P Kenny
Aug 24, 2004·Journal of Applied Physiology·Brad W WilkinsJohn R Halliwill
Nov 13, 2004·The Journal of Physiology·S DurandC G Crandall
Sep 30, 2006·The Journal of Physiology·David M KellerCraig G Crandall
Jul 29, 2006·European Journal of Applied Physiology·Ashild O Miland, James B Mercer
Jul 12, 2007·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Glen P KennyW Shane Journeay
Nov 5, 2008·Medicine and Science in Sports and Exercise·Craig G Crandall
Jan 14, 2009·The Journal of Physiology·David M KellerCraig G Crandall
Dec 16, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Aaron G LynnGlen P Kenny
Apr 20, 2014·Physiological Reports·Juliana Barrera-RamirezGlen P Kenny
Dec 3, 2016·Physiological Reports·Bryce N BalmainNorman R Morris
Feb 14, 1998·Journal of Applied Physiology·K L RyanV S Bishop
Nov 5, 2003·Journal of Applied Physiology·Glaucio Scremin, W Larry Kenney
Apr 4, 1998·Medicine and Science in Sports and Exercise·J M Johnson
Oct 23, 2002·Journal of Applied Physiology·Robert CarterCraig G Crandall
Oct 23, 2002·Journal of Applied Physiology·Manabu ShibasakiCraig G Crandall
Jul 25, 2007·Sports Medicine·Daniël WendtWouter D van Marken Lichtenbelt
Apr 13, 2004·Journal of Applied Physiology·Thad E WilsonChester A Ray
Sep 20, 2008·Journal of Applied Physiology·Manabu ShibasakiCraig G Crandall
Oct 20, 2007·The Journal of Physiology·Manabu ShibasakiCraig G Crandall
Aug 10, 2010·American Journal of Physiology. Heart and Circulatory Physiology·C G CrandallT E Wilson
Nov 26, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Michael J Joyner
Oct 9, 2014·Physiological Reports·Ryan McGinnGlen P Kenny
May 3, 2013·European Journal of Applied Physiology·W Larry KenneyLacy M Alexander
Oct 26, 2014·Physiological Reports·Matthew J Heffernan, Matthew D Muller
Oct 24, 2015·Journal of Applied Physiology·Jody L GreaneyW Larry Kenney
Sep 29, 2000·American Journal of Physiology. Heart and Circulatory Physiology·C G Crandall
May 29, 2002·Anesthesia and Analgesia·Yasufumi NakajimaToshiki Mizobe
Nov 15, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ryan McGinnGlen P Kenny
Aug 5, 2016·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Davor KrnjajicDavid M Keller
Jul 14, 2017·Journal of Neurophysiology·Jody L Greaney, W Larry Kenney
Aug 24, 2017·The Journal of Physiology·Daniel GagnonCraig G Crandall

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