Barosensory cells in the nucleus tractus solitarius receive convergent input from group III muscle afferents and central command

Neuroscience
Alexandr M Degtyarenko, Marc P Kaufman

Abstract

Some neural mechanism must prevent the full expression of the baroreceptor reflex during static exercise because arterial blood pressure increases even though the baroreceptors are functioning. Two likely candidates are central command and input from the thin fiber muscle afferents evoking the exercise pressor reflex. Recently, activation of the mesencephalic locomotor region, an anatomical locus for central command, was found to inhibit the discharge of nucleus tractus solitarius cells that were stimulated by arterial baroreceptors in decerebrated cats. In contrast, the effect of thin fiber muscle afferent input on the discharge of nucleus tractus solitarius cells stimulated by baroreceptors is not known. Consequently in decerebrated unanesthetized cats, we examined the responses of barosensory nucleus tractus solitarius cells to stimulation of thin fiber muscle afferents and to stimulation of the mesencephalic locomotor region, a maneuver which evoked fictive locomotion. We found that electrical stimulation of either the mesencephalic locomotor region or the gastrocnemius nerve at current intensities that recruited group III afferents inhibited the discharge of nucleus tractus solitarius cells receiving baroreceptor input. We...Continue Reading

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Citations

Jun 26, 2010·Exercise and Sport Sciences Reviews·Chao-Yin Chen, Ann C Bonham
Jan 11, 2011·American Journal of Physiology. Heart and Circulatory Physiology·Masaki MizunoScott A Smith
Mar 6, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Chao-Yin ChenAnn C Bonham
Feb 10, 2010·The Journal of Physiology·James P FisherPaul J Fadel
Jun 5, 2013·Experimental Physiology·Jody L GreaneyWilliam B Farquhar
Apr 23, 2014·Scandinavian Journal of Medicine & Science in Sports·M M LawrenceR Howden
Apr 6, 2016·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Alessandro SilvaniPietro Cortelli
Sep 5, 2013·Autonomic Neuroscience : Basic & Clinical·Kanji MatsukawaNan Liang
May 27, 2016·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Zhi-Ling GuoLiang-Wu Fu
Jun 28, 2018·Journal of Neurophysiology·Jeann L Sabino-CarvalhoLauro C Vianna
Mar 11, 2008·American Journal of Physiology. Heart and Circulatory Physiology·James P FisherPaul J Fadel
Sep 6, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Julia Shanks, Neil Herring
Mar 7, 2014·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Kanji MatsukawaNan Liang
Sep 19, 2014·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Stephanie C Tjen-A-LooiJohn C Longhurst
Nov 3, 2016·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Thales C BarbosaNiels H Secher
Feb 27, 2010·Journal of Applied Physiology·Mikael SanderLuke A Henderson
Aug 7, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Shigehiko OgohPaul J Fadel
Jun 23, 2007·Journal of Applied Physiology·James P FisherPaul J Fadel

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