Barrett's esophagus: current and future role of endosonography and optical coherence tomography

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
S A FaruqiM S Bhutani

Abstract

This paper reviews the role of endosonography and optical coherence tomography (OCT) for imaging of Barrett's esophagus (BE). The routine use of endoscopic ultrasound (EUS) to screen patients with BE is neither justified nor cost effective. EUS does appear to have a role in patients who have BE and high-grade dysplasia or intramucosal carcinoma, in whom a non-operative therapy is being contemplated. For patients with a diagnosis of esophageal cancer with or without BE, EUS is superior to computed tomography or magnetic resonance imaging for assessing esophageal wall penetration and for detecting regional lymph node involvement. In its current state, OCT is not yet ready for application in clinical practice. However, given its superior resolution compared with other modalities such as EUS, OCT has great potential as a powerful adjunct to standard endoscopy in surveillance of BE and may enhance the ability of endoscopists to detect high-grade dysplasia at an early stage. With further technical refinement, this technique may become a mainstay in the surveillance of BE and other premalignant conditions of the gastrointestinal tract.

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Citations

Feb 19, 2005·Journal of Clinical Gastroenterology·Herbert C Wolfsen
Nov 26, 2008·World Journal of Gastroenterology : WJG·Pier-Alberto Testoni, Benedetto Mangiavillano
Jan 11, 2011·World Journal of Gastroenterology : WJG·Eugen OsiacRadu Angelescu
Nov 13, 2007·Journal of Biomedical Optics·Adam M ZyskStephen A Boppart
Feb 14, 2008·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·A D SavoyM B Wallace
Oct 21, 2011·World Journal of Gastrointestinal Endoscopy·Richa ShuklaSharmila Anandasabapathy
Mar 12, 2009·Expert Review of Anticancer Therapy·Jennifer D McAllasterMazin Al-Kasspooles
Oct 18, 2006·Journal of Public Health Policy·Ben SheppardSimon Wessely

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