Barriers and facilitators to healthcare professional behaviour change in clinical trials using the Theoretical Domains Framework: a case study of a trial of individualized temperature-reduced haemodialysis

Trials
Justin PresseauMajor outcomes with personalized dialysate TEMPerature (MyTEMP) investigators

Abstract

Implementing the treatment arm of a clinical trial often requires changes to healthcare practices. Barriers to such changes may undermine the delivery of the treatment making it more likely that the trial will demonstrate no treatment effect. The 'Major outcomes with personalized dialysate temperature' (MyTEMP) is a cluster-randomised trial to be conducted in 84 haemodialysis centres across Ontario, Canada to investigate whether there is a difference in major outcomes with an individualized dialysis temperature (IDT) of 0.5 °C below a patient's body temperature measured at the beginning of each haemodialysis session, compared to a standard dialysis temperature of 36.5 °C. To inform how to deploy the IDT across many haemodialysis centres, we assessed haemodialysis physicians' and nurses' perceived barriers and enablers to IDT use. We developed two topic guides using the Theoretical Domains Framework (TDF) to assess perceived barriers and enablers to IDT ordering and IDT setting (physician and nurse behaviours, respectively). We recruited a purposive sample of haemodialysis physicians and nurses from across Ontario and conducted in-person or telephone interviews. We used directed content analysis to double-code transcribed uttera...Continue Reading

Associated Clinical Trials

References

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Citations

Apr 12, 2018·Academic Medicine : Journal of the Association of American Medical Colleges·Dahn JeongSimon Kitto
Mar 10, 2020·International Wound Journal·Carolina D WellerVictoria Team
Jul 6, 2019·The Cochrane Database of Systematic Reviews·Yasushi TsujimotoShunichi Fukuhara
Jul 1, 2020·BMC Health Services Research·L RogersE McAuliffe
Nov 28, 2018·Current Opinion in Nephrology and Hypertension·Ron WaldMichael W Walsh

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Clinical Trials Mentioned

NCT02628366

Software Mentioned

Dialysis
MyTEMP
NVivo

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