Barriers and motivations for women to participate in cardiovascular trials.

Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC
Angela M CheungDonna E Stewart

Abstract

Cardiovascular disease is one of the major causes of mortality in Canadian women. However, the number of women recruited into cardiovascular clinical trials continues to be low relative to the prevalence of cardiovascular disease. To determine why the recruitment of women into cardiovascular trials continues to be problematic, we prospectively examined the barriers and motivations of women contacted for the Raloxifene Use for The Heart (RUTH) study. Two hundred seventy postmenopausal women were surveyed. Regardless of study eligibility, women were asked to comment on their reasons for participating or not participating in cardiovascular trials in an open-ended single question format. All answers were recorded and grouped accordingly. Fifty-four percent of women surveyed indicated they would not participate in clinical research, and 46% indicated that they would. Motivations reported for participating in a cardiovascular clinical trial included personal health benefits (82.2%), interest in research (44.1%), and the possibility of benefiting society (29.1%). Reasons for declining participation included personal illness (24.8%), transportation issues (17.9%), reluctance to increase medication (15.2%), and concern about adverse hea...Continue Reading

Citations

Mar 5, 2016·Social Work in Health Care·Michael C SouleJeff C Huffman
Nov 23, 2010·Journal of Epidemiology·Rafael J A CámaraUNKNOWN Swiss Inflammatory Bowel Disease Cohort Study Group
Dec 3, 2016·Journal of Parkinson's Disease·Lauren HeusinkveldDavid Charles
Jun 17, 2020·Journal of Women's Health·Mohammed Imran GhareAlexandra Lansky
Jul 19, 2011·PloS One·Prema MenezesJoseph J Eron
Dec 22, 2020·American Journal of Obstetrics & Gynecology MFM·Megha GuptaSuneet P Chauhan
Aug 6, 2021·European Heart Journal·Jeske van DiemenYolande Appelman
Oct 2, 2021·European Heart Journal. Quality of Care & Clinical Outcomes·Yvonne Mei Fong LimStefan Koudstaal

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