Abstract
Although monitoring of cytogenetic/molecular responses to therapy in chronic myelogenous leukemia (CML) facilitates superior outcomes, less than one half of CML patients are monitored using published evidence-based guidelines. Barriers to physician adherence with guidelines are unknown. An anonymous survey was mailed to 515 hematologist-oncologists in New Jersey and Indiana exploring attitudes toward monitoring guidelines. Ninety-six physicians (19%) responded-89% in community practice, 83% with more than 10 years of experience, and 92% caring for CML patients. Eighty-four percent self-reported using CML monitoring guidelines, 14% were familiar with but did not adopt guidelines and 2% were unfamiliar. Eighty-four percent performed molecular monitoring quarterly as recommended; 6% did not perform molecular monitoring at all during the first year. Guidelines were considered evidence based by 98%, but only 54% strongly considered them easy to find; only 51% strongly felt they addressed all aspects of disease management. Patient resource barriers were a significant deterrent toward implementation with 30% citing high costs. Physician resources, including lack of time to search guidelines, limited use in one fifth. Despite 90% belie...Continue Reading
References
Oct 27, 1999·JAMA : the Journal of the American Medical Association·M D CabanaH R Rubin
Mar 10, 2005·JAMA : the Journal of the American Medical Association·Amit X GargR Brian Haynes
Aug 23, 2005·International Journal of Technology Assessment in Health Care·Bernard S Bloom
Jul 5, 2008·Annals of Surgical Oncology·Jennifer Erickson FosterTina J Hieken
Dec 22, 2010·Archives of Otolaryngology--head & Neck Surgery·Carol M LewisRandal S Weber
Nov 10, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·David MarinLetizia Foroni
Feb 7, 2012·American Journal of Clinical Oncology·Howard KormanFrank A Vicini
Feb 23, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ryaz ChagparJanice N Cormier
Mar 27, 2012·Leukemia·B HanfsteinUNKNOWN German CML Study Group
May 31, 2012·International Journal of Colorectal Disease·Rebecca A LevineHarry Wasvary
Jul 6, 2012·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Brendan C VisserKim F Rhoads
Dec 14, 2012·BMC Health Services Research·Pille TabaLisa Bero
Jan 3, 2013·Cancer·Genevieve M BolandJanice N Cormier
Apr 27, 2013·Blood·UNKNOWN Experts in Chronic Myeloid Leukemia
Jun 7, 2013·Current Medical Research and Opinion·Stuart L GoldbergEric Q Wu
Jun 28, 2013·Blood·Michele BaccaraniRüdiger Hehlmann
Oct 22, 2013·BMC Cancer·Lukas SchwentnerUNKNOWN Brenda study group
Nov 6, 2013·Journal of Medical Economics·Annie GuérinStuart L Goldberg
Nov 15, 2013·Journal of the National Comprehensive Cancer Network : JNCCN·Susan O'BrienUNKNOWN Ntational comprehensive cancer network
Dec 25, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stacie B DusetzinaNancy L Keating
Jan 21, 2014·Journal of Oncology Practice·J Russell HovermanMarcus Neubauer
Jan 28, 2014·Journal of Surgical Oncology·Sanjay P BagariaNabil Wasif
Mar 20, 2014·Current Medical Research and Opinion·Annie GuérinStuart L Goldberg
Citations
Oct 21, 2015·Leukemia & Lymphoma·Patricia KropfJean-Pierre J Issa
Oct 5, 2015·Clinical Lymphoma, Myeloma & Leukemia·Stuart L Goldberg
Apr 18, 2016·Journal of Cancer Research and Clinical Oncology·Qian Jiang, Robert Peter Gale
Apr 10, 2016·American Journal of Hematology·Daniel Egan, Jerald Radich
Jul 16, 2016·Healthcare·Florian FischerAlexander Kraemer
Aug 6, 2010·Critical Reviews in Oncology/hematology·Massimo Breccia, Giuliana Alimena
Jan 27, 2017·Journal of Managed Care & Specialty Pharmacy·Dominick Latremouille-ViauGeorge J Joseph
Nov 14, 2018·Journal of Oncology Practice·Karen SweissPritesh R Patel
Jan 23, 2019·Leukemia & Lymphoma·Geneviève I C G EctorNicole M A Blijlevens
Aug 2, 2019·The International Journal of Health Planning and Management·Jianwei ShiZhaoxin Wang
Sep 23, 2018·Journal of Global Oncology·Uday YanamandraSubhash Varma
Oct 12, 2019·JAMA Network Open·Jessica I BilligKevin C Chung
Aug 18, 2017·American Journal of Hematology·Stuart L GoldbergMichael J Mauro
Feb 10, 2021·Schizophrenia Research·Gabriele GaiglAlkomiet Hasan