Basal and stimulated levels of prolactin, TSH and LH in serum of chronic schizophrenic patients, long-term treated with neuroleptics

Pharmakopsychiatrie, Neuro-Psychopharmakologie
D NaberK von Werder

Abstract

Basal and stimulated (0.2 mg TRH, 0.025 mg LHRH) levels of prolactin, TSH and LH were measured in serum of 12 male and 10 female chronic schizophrenic patients, hospitalized and treated with neuroleptics from 6-21 years. The mean values of the 3 pituitary hormones were within the normal range in both sexes. Tolerance to the prolactin increasing effect of neuroleptics appears to develop after long-term neuroleptic treatment. TSH and LH secretion are not markedly impaired by chronic neuroleptic treatment.

Citations

Apr 1, 1992·Biological Psychiatry·M Bommer, D Naber
Jan 1, 1989·Psychoneuroendocrinology·J R MagliozziJ N Laubly
Jan 1, 1982·Psychoneuroendocrinology·D A CarterS A Whitehead
Jan 1, 1993·European Archives of Psychiatry and Clinical Neuroscience·A Riecher-Rössler, H Häfner
Sep 1, 1984·The British Journal of Psychiatry : the Journal of Mental Science·W GreilE Rüther
Mar 1, 1983·British Journal of Clinical Pharmacology·D J KingJ Liddle

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