Basal cell carcinoma of the scalp with destruction and invasion into the calvarium and dura mater: Report of 7 cases and review of literature

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Churl-Su KwonSaulius Rocka

Abstract

Basal cell carcinoma (BCC) is the most common skin malignancy in humans. Giant BCC is a rarer entity that is characterised by aggressive biological behaviour. Intracranial invasion by a BCC on the scalp is extremely rare. The gold standard treatment of BCCs is represented by surgical excision with a wide variety of reconstructive techniques. In this paper, we describe the largest series to date of recurrent BCCs with intracranial extension involving the dura mater. We report recurrent giant BCC of the scalp with dura mater invasion in 7 patients. All patients in this series previously had more than 2 operations. Gadolinium-enhanced MRI revealed neoplastic invasion of the meninges and brain tissues. All patients had a multi-disciplinary team approach with the surgical margins ranging between 1 and 2 cm depending on the location and the size of the tumour. 5 of the patients underwent reconstruction of the skin defect by antero-lateral thigh flap, 1 patient underwent reconstruction with pedicled myocutaneous (trapezius) flap, and 1 with a pedicled myocutaneous latissimus dorsi flap. There was a mean follow-up of 5.3 years. 2 patients died due to cardio-pulmonary complications in the neuro-intensive care unit. A multi-disciplinary ...Continue Reading

Citations

Jul 28, 2019·The Journal of Craniofacial Surgery·Stephan BarrientosShannon Wong
Aug 11, 2020·Archives of Dermatological Research·Karina FurlanPaolo Gattuso
Mar 3, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·E DikaM Lambertini
Oct 3, 2019·The Journal of Craniofacial Surgery·Stephan BarrientosShannon Wong
Feb 26, 2021·Case Reports in Radiology·Maria Brunella CipulloSotirios Bisdas
Jul 22, 2019·Journal of Stomatology, Oral and Maxillofacial Surgery·N Ben SlamaO Trost

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