PMID: 9631996Jun 19, 1998Paper

Basal cell carcinoma with ossification

Journal of the American Academy of Dermatology
A S Boyd, L E King

Abstract

Osteoma cutis, the presence of lamellar bone in the skin, is relatively common. This process is divided into two categories: primary osteoma cutis and secondary osteoma cutis. The purpose of this study was to describe the clinical and histopathologic features of patients in whom lamellar bone developed in cutaneous basal cell carcinoma. We evaluated the features of five cases of osteoma cutis associated with basal cell carcinoma and obtained detailed clinical information from those patients. All five patients had significant underlying medical conditions, including two patients who were receiving interferon alfa-2b therapy. Three patients had been previously treated with electrodesiccation and curettage. The amount of sun exposure experienced by these patients varied. Histologically, the basal cell carcinomas were of the nodular or micronodular variety. Bone was found both in the stroma and intratumorally. The presence of bone within basal cell carcinomas is not uncommon and may be more prevalent in patients with an underlying medical disorder.

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Citations

Jul 27, 2010·Archives of Dermatological Research·Jeannette TothPecorella Irene
Nov 28, 2002·The American Journal of Dermatopathology·Phillip A ConlinRonald P Rapini
Jul 2, 2003·Plastic and Reconstructive Surgery·Ivan Depasquale, Venkat Ramakrishnan
Nov 30, 2011·The American Journal of Dermatopathology·Alan S Boyd
Sep 30, 2008·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Hidehiko KuribayashiYoshihiro Matsuno
Dec 13, 2012·International Journal of Dermatology·Takenobu OhashiMasayuki Okochi
Nov 20, 2014·Journal of Cutaneous Pathology·Solomon S LeePaul B Googe
Dec 7, 2019·Ophthalmic Plastic and Reconstructive Surgery·Lauren R SchafferHans E Grossniklaus
Jun 4, 2018·Dermatology and Therapy·Barbara J CohenPhilip R Cohen

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Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

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