PMID: 11331629May 2, 2001Paper

Basal concentrations of oestradiol may predict the outcome of in-vitro maturation in regularly menstruating women

Human Reproduction
Anne Lis MikkelsenS Lindenberg

Abstract

Retrospectively it was examined whether the number of retrieved oocytes, the maturation rate and cleavage rate can be predicted in regularly menstruating women by the use of the following predictive variables on cycle day 3-4: the concentration of FSH, oestradiol, inhibin B and inhibin A in serum and and the number of ovarian follicles seen by vaginal ultrasound. The study included 132 consecutive aspirations in 100 women attending the clinic for in-vitro maturation due to male factor and/or tubal factor. Fifteen pregnancies were obtained after transfer in 83 cycles, giving a pregnancy rate of 15/132 (11%) per aspiration and 15/83 (18%) per transfer. The concentration of FSH and the number of follicles on day 3 predicted the number of oocytes retrieved, whereas these parameters did not predict the subsequent development of oocytes. No correlation was found between the inhibin B, inhibin A, oestradiol and the number of oocytes respectively. The group with a low concentration of oestradiol on cycle day 3 (threshold <200 pmol/l) (group 1, n = 106 cycles) had a significantly higher pregnancy rate compared to the group with a higher concentration (group 2, n = 26 cycles) (14 versus 0% per aspiration, P = 0.03). The group with a low ...Continue Reading

References

Dec 1, 1987·The Journal of Clinical Endocrinology and Metabolism·S J RichardsonJ F Nelson
Dec 1, 1995·Fertility and Sterility·C H SyropB J Van Voorhis
Jun 1, 1996·Fertility and Sterility·F L BarnesA Trounson
Jan 1, 1997·Fertility and Sterility·D B SeiferC A Berk
Apr 1, 1997·Fertility and Sterility·J B RussellJ A Dickson
Sep 19, 1998·Human Reproduction Update·G M LockwoodW L Ledger
Oct 2, 1998·Human Reproduction·A TrounsonC Wood
Nov 5, 1999·Human Reproduction·S L CorsonM R Soules
Feb 26, 2000·Fertility and Sterility·S D SmithS Lindenberg

❮ Previous
Next ❯

Citations

Mar 26, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Outi Hovatta
Sep 24, 2004·Gynécologie, obstétrique & fertilité·C Coussieu
May 29, 2002·Current Opinion in Obstetrics & Gynecology·Helen M Picton
Feb 9, 2013·Fertility and Sterility·UNKNOWN Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology
Jan 9, 2007·Reproductive Biomedicine Online·Chikako SatoTakafumi Utsunomiya
Aug 10, 2006·Reproductive Biomedicine Online·M B Dal CantoR Fadini
Dec 1, 2004·Human Reproduction Update·Kerryn Lutchman SinghRatna Chatterjee
Feb 8, 2005·Human Reproduction·Viveca Söderström-AnttilaAnne-Maria Suikkari
Jan 23, 2008·Gynäkologisch-geburtshilfliche Rundschau·Michael von WolffThomas Strowitzki
Jan 8, 2004·Clinical Chemistry·Zhimin CaoRobert Rej
Aug 8, 2006·Human Reproduction Update·F J BroekmansC B Lambalk
Jan 27, 2015·Obstetrical & Gynecological Survey·May-Tal Sauerbrun-CutlerPeter G McGovern

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.